-transparent.png){kind=logo}
This study includes the first systematic comparison of an organic nitrate with the corresponding organic nitrite-isobutyl nitrate and isobutyl nitrite. The spasmolytic activity of the nitrite on isolated rabbit aortic strips was stronger, more rapid in onset, but less stable than the activity of the nitrate. In vitro tolerance to glyceryl trinitrate and isobutyl nitrite greatly weakened the activity of isobutyl nitrate, respectively, but had much less effect on isobutyl nitrite. Possible reasons for these differences are discussed.
Related Publications
T Zimmermann, and
M Leitold, and
R A Yeates
January 2005,
Pharmacology & therapeutics,
T Zimmermann, and
M Leitold, and
R A Yeates
January 1966,
Journal of pharmaceutical sciences,
T Zimmermann, and
M Leitold, and
R A Yeates
January 1970,
The Journal of pharmacology and experimental therapeutics,
T Zimmermann, and
M Leitold, and
R A Yeates
April 1987,
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
T Zimmermann, and
M Leitold, and
R A Yeates
May 1988,
Pharmacology & toxicology,
T Zimmermann, and
M Leitold, and
R A Yeates
March 1980,
Circulation,
T Zimmermann, and
M Leitold, and
R A Yeates
April 1985,
The American journal of cardiology,
T Zimmermann, and
M Leitold, and
R A Yeates
February 1987,
British medical journal (Clinical research ed.),
T Zimmermann, and
M Leitold, and
R A Yeates
January 1968,
Archives internationales de pharmacodynamie et de therapie,
T Zimmermann, and
M Leitold, and
R A Yeates
February 1973,
European journal of pharmacology,
