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Antiphospholipid syndrome (APS) is an acquired autoimmune thrombophilia diagnosed based on the presence of a single clinical sign (thrombosis or and obstetric problem) and one serological criterion (anticardiolipin antibodies and/or lupoid anticoagulant and/or antibodies against b2-glycoprotein-1. Clinical feature of the syndrome are diverse and depend on localization and diameter of the affected Bessel. This review focuses on cardiovascular aspects of APS. Cradiovascular system disorders are arbitrarily divided into valvular pathology, coronary and myocardial lesions. The relationship between antiphospholoipid antibodies and atherosclerosis is discussed.
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