[The patient with chronic renal failure]. 2008

Theodora Schammann, and Ralf Schindler
Abt. Nephrologie und Internistische Intensivmedizin, Charité, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin.

Reduced renal function probably affects more people than is known. While there are "only" 66,000 dialysis patients in germany, there are few data on the prevalence of less severe renal failure. Renal failure is becoming a problem of the elderly. The highest rates in dialysis patients are reported for people above 65. In the elderly, the two most important causes of renal failure (type II diabetes and hypertension) are present in great numbers. Therapy of terminal renal failure consists of hemodialysis, peritoneal dialysis or kidney transplantation. Before reaching dialysis, the therapy concentrates on correction of calcium-phosphate balance, acidosis, anemia and hypertension. Because many drugs are eliminated via the kidney, the knowledge of renal function is of eminent importance for the pharmacist.

UI MeSH Term Description Entries
D007676 Kidney Failure, Chronic The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION. ESRD,End-Stage Renal Disease,Renal Disease, End-Stage,Renal Failure, Chronic,Renal Failure, End-Stage,Chronic Kidney Failure,End-Stage Kidney Disease,Chronic Renal Failure,Disease, End-Stage Kidney,Disease, End-Stage Renal,End Stage Kidney Disease,End Stage Renal Disease,End-Stage Renal Failure,Kidney Disease, End-Stage,Renal Disease, End Stage,Renal Failure, End Stage
D010530 Peritoneal Dialysis Dialysis fluid being introduced into and removed from the peritoneal cavity as either a continuous or an intermittent procedure. Dialyses, Peritoneal,Dialysis, Peritoneal,Peritoneal Dialyses
D006435 Renal Dialysis Therapy for the insufficient cleansing of the BLOOD by the kidneys based on dialysis and including hemodialysis, PERITONEAL DIALYSIS, and HEMODIAFILTRATION. Dialysis, Extracorporeal,Dialysis, Renal,Extracorporeal Dialysis,Hemodialysis,Dialyses, Extracorporeal,Dialyses, Renal,Extracorporeal Dialyses,Hemodialyses,Renal Dialyses
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

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