BIOMAT Database Logo BIOMAT Database Logo

[Effect, recurrence and prognosis of intra-arterial infusion chemotherapy with anticancer agents for advanced breast cancer--especially, the significance of tumor blood vessels]. 1991

K Toda, and K Asaishi, and M Okazaki, and H Masuoka, and A Okazaki, and Y Watanabe, and H Sato, and T Mikami, and S Ohba, and Y Okazaki
1st Dept. of Surgery, Sapporo Medical College.

Between January 1977 and March 1991, 86 patients of Stage III and Stage IV breast cancer were treated by intra-arterial infusion chemotherapy (IAIC) in Sapporo Medical College. The 5- and 10-year overall survival rates of Stage III b were: infusion group 53.1% and 53.1%, non infusion group 50.1% and 16.7%, respectively. A significant difference was seen in the 10-year survival rate (p less than 0.05). The 5- and 10-year overall survival rate of Stage III b histologically effective group was 67.3% and non-effective group 31.8%. A significant difference was seen between these two groups (p = 0.0241). A significant difference was seen between n2 positive Stage III b infusion group and non-infusion group in 7-year survival rate (p less than 0.01). The ischemic effect on tumor cells by degeneration changes of the blood vessels was important for the histological effect. Pre-operative angiography helped in the choice of anticancer agents. The sufficient adjuvant chemo-endocrine therapy will assure a good prognosis for IAIC-treated Stage III b breast cancer patients.

UI MeSH Term Description Entries
D007261 Infusions, Intra-Arterial Regional infusion of drugs via an arterial catheter. Often a pump is used to impel the drug through the catheter. Used in therapy of cancer, upper gastrointestinal hemorrhage, infection, and peripheral vascular disease. Infusions, Regional Arterial,Infusions, Intra Arterial,Infusions, Intraarterial,Arterial Infusion, Intra,Arterial Infusion, Regional,Arterial Infusions, Intra,Arterial Infusions, Regional,Infusion, Intra Arterial,Infusion, Intra-Arterial,Infusion, Intraarterial,Infusion, Regional Arterial,Intra Arterial Infusion,Intra Arterial Infusions,Intra-Arterial Infusion,Intra-Arterial Infusions,Intraarterial Infusion,Intraarterial Infusions,Regional Arterial Infusion,Regional Arterial Infusions
D008207 Lymphatic Metastasis Transfer of a neoplasm from its primary site to lymph nodes or to distant parts of the body by way of the lymphatic system. Lymph Node Metastasis,Lymph Node Metastases,Lymphatic Metastases,Metastasis, Lymph Node
D008937 Mitomycins A group of methylazirinopyrroloindolediones obtained from certain Streptomyces strains. They are very toxic antibiotics used as ANTINEOPLASTIC AGENTS in some solid tumors. PORFIROMYCIN and MITOMYCIN are the most useful members of the group.
D009367 Neoplasm Staging Methods which attempt to express in replicable terms the extent of the neoplasm in the patient. Cancer Staging,Staging, Neoplasm,Tumor Staging,TNM Classification,TNM Staging,TNM Staging System,Classification, TNM,Classifications, TNM,Staging System, TNM,Staging Systems, TNM,Staging, Cancer,Staging, TNM,Staging, Tumor,System, TNM Staging,Systems, TNM Staging,TNM Classifications,TNM Staging Systems
D011379 Prognosis A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations. Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D001943 Breast Neoplasms Tumors or cancer of the human BREAST. Breast Cancer,Breast Tumors,Cancer of Breast,Breast Carcinoma,Cancer of the Breast,Human Mammary Carcinoma,Malignant Neoplasm of Breast,Malignant Tumor of Breast,Mammary Cancer,Mammary Carcinoma, Human,Mammary Neoplasm, Human,Mammary Neoplasms, Human,Neoplasms, Breast,Tumors, Breast,Breast Carcinomas,Breast Malignant Neoplasm,Breast Malignant Neoplasms,Breast Malignant Tumor,Breast Malignant Tumors,Breast Neoplasm,Breast Tumor,Cancer, Breast,Cancer, Mammary,Cancers, Mammary,Carcinoma, Breast,Carcinoma, Human Mammary,Carcinomas, Breast,Carcinomas, Human Mammary,Human Mammary Carcinomas,Human Mammary Neoplasm,Human Mammary Neoplasms,Mammary Cancers,Mammary Carcinomas, Human,Neoplasm, Breast,Neoplasm, Human Mammary,Neoplasms, Human Mammary,Tumor, Breast
D004317 Doxorubicin Antineoplastic antibiotic obtained from Streptomyces peucetius. It is a hydroxy derivative of DAUNORUBICIN. Adriamycin,Adriablastin,Adriablastine,Adriblastin,Adriblastina,Adriblastine,Adrimedac,DOXO-cell,Doxolem,Doxorubicin Hexal,Doxorubicin Hydrochloride,Doxorubicin NC,Doxorubicina Ferrer Farm,Doxorubicina Funk,Doxorubicina Tedec,Doxorubicine Baxter,Doxotec,Farmiblastina,Myocet,Onkodox,Ribodoxo,Rubex,Urokit Doxo-cell,DOXO cell,Hydrochloride, Doxorubicin,Urokit Doxo cell
D005260 Female Females
D005472 Fluorouracil A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid. 5-FU,5-FU Lederle,5-FU Medac,5-Fluorouracil,5-Fluorouracil-Biosyn,5-HU Hexal,5FU,Adrucil,Carac,Efudex,Efudix,Fluoro-Uracile ICN,Fluoroplex,Fluorouracil Mononitrate,Fluorouracil Monopotassium Salt,Fluorouracil Monosodium Salt,Fluorouracil Potassium Salt,Fluorouracil-GRY,Fluorouracile Dakota,Fluorouracilo Ferrer Far,Fluoruracil,Fluracedyl,Flurodex,Haemato-FU,Neofluor,Onkofluor,Ribofluor,5 FU Lederle,5 FU Medac,5 Fluorouracil,5 Fluorouracil Biosyn,5 HU Hexal,Dakota, Fluorouracile,Fluoro Uracile ICN,Fluorouracil GRY,Haemato FU
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

K Toda, and K Asaishi, and M Okazaki, and H Masuoka, and A Okazaki, and Y Watanabe, and H Sato, and T Mikami, and S Ohba, and Y Okazaki
[Intra-arterial infusion chemotherapy with epirubicin for advanced breast cancer].
June 1991, Gan to kagaku ryoho. Cancer & chemotherapy,
K Toda, and K Asaishi, and M Okazaki, and H Masuoka, and A Okazaki, and Y Watanabe, and H Sato, and T Mikami, and S Ohba, and Y Okazaki
[Intra-arterial infusion chemotherapy with docetaxel for locally advanced breast cancer and inflammatory breast cancer].
October 2000, Gan to kagaku ryoho. Cancer & chemotherapy,
K Toda, and K Asaishi, and M Okazaki, and H Masuoka, and A Okazaki, and Y Watanabe, and H Sato, and T Mikami, and S Ohba, and Y Okazaki
[Prognostic significance of intra-arterial infusion chemotherapy in the treatment of locally advanced breast cancer].
August 1989, Gan to kagaku ryoho. Cancer & chemotherapy,
K Toda, and K Asaishi, and M Okazaki, and H Masuoka, and A Okazaki, and Y Watanabe, and H Sato, and T Mikami, and S Ohba, and Y Okazaki
Intra-arterial cancer chemotherapy with combined anticancer agents.
March 1973, The Japanese journal of surgery,
K Toda, and K Asaishi, and M Okazaki, and H Masuoka, and A Okazaki, and Y Watanabe, and H Sato, and T Mikami, and S Ohba, and Y Okazaki
[Intra-arterial infusion chemotherapy for breast cancer].
September 1996, Gan to kagaku ryoho. Cancer & chemotherapy,
K Toda, and K Asaishi, and M Okazaki, and H Masuoka, and A Okazaki, and Y Watanabe, and H Sato, and T Mikami, and S Ohba, and Y Okazaki
[Intra-arterial infusion chemotherapy for breast cancer].
February 2002, Gan to kagaku ryoho. Cancer & chemotherapy,
K Toda, and K Asaishi, and M Okazaki, and H Masuoka, and A Okazaki, and Y Watanabe, and H Sato, and T Mikami, and S Ohba, and Y Okazaki
[Intra-arterial infusion chemotherapy of locally advanced and recurrent breast cancer].
August 1989, Gan to kagaku ryoho. Cancer & chemotherapy,
K Toda, and K Asaishi, and M Okazaki, and H Masuoka, and A Okazaki, and Y Watanabe, and H Sato, and T Mikami, and S Ohba, and Y Okazaki
Clinical significance of preoperative regional intra-arterial infusion chemotherapy for advanced gastric cancer.
October 2004, World journal of gastroenterology,
K Toda, and K Asaishi, and M Okazaki, and H Masuoka, and A Okazaki, and Y Watanabe, and H Sato, and T Mikami, and S Ohba, and Y Okazaki
[Effect of angiotensin II in intra-arterial infusion chemotherapy of locally advanced breast cancer].
April 1985, Nihon Gan Chiryo Gakkai shi,
K Toda, and K Asaishi, and M Okazaki, and H Masuoka, and A Okazaki, and Y Watanabe, and H Sato, and T Mikami, and S Ohba, and Y Okazaki
Intra-arterial infusion chemotherapy in the treatment of locally advanced breast cancer.
January 1997, Acta oncologica (Stockholm, Sweden),
Copied contents to your clipboard!