Biomaterial Database

[Chemical constituents from herbs of Swertia delavayi]. 2008

Cong-long Xia, and Guang-ming Liu, and Hao Zhang

Department of Pharmacy, Dali University, Dali 671000, China. long7484@126.com

OBJECTIVE To isolate and identify the chemical constituents of 95% alcohol extract from Swertia delavayi. METHODS The compounds were isolated and purified by column chromatogrphy and their structures were identified by the physicochemical properties and spectral analyses. RESULTS Seven compounds were isolated and identified as oleanolic acid (1), gentiopcroside (2), swertiamarin (3), daucosterol (4), swertiadecoraxanthone-II (5), isovitexin (6), isoorientin (7). CONCLUSIONS Compounds 2-7 were isolated from S. delavayi for the first time. While the compound 6 was firstly reported from the genus Swertia.

UI	MeSH Term	Description	Entries
D009682	Magnetic Resonance Spectroscopy	Spectroscopic method of measuring the magnetic moment of elementary particles such as atomic nuclei, protons or electrons. It is employed in clinical applications such as NMR Tomography (MAGNETIC RESONANCE IMAGING).	In Vivo NMR Spectroscopy,MR Spectroscopy,Magnetic Resonance,NMR Spectroscopy,NMR Spectroscopy, In Vivo,Nuclear Magnetic Resonance,Spectroscopy, Magnetic Resonance,Spectroscopy, NMR,Spectroscopy, Nuclear Magnetic Resonance,Magnetic Resonance Spectroscopies,Magnetic Resonance, Nuclear,NMR Spectroscopies,Resonance Spectroscopy, Magnetic,Resonance, Magnetic,Resonance, Nuclear Magnetic,Spectroscopies, NMR,Spectroscopy, MR
D009828	Oleanolic Acid	A pentacyclic triterpene that occurs widely in many PLANTS as the free acid or the aglycone for many SAPONINS. It is biosynthesized from lupane. It can rearrange to the isomer, ursolic acid, or be oxidized to taraxasterol and amyrin.	Oleanol,Hederins,Oleanane Triterpenes,Triterpenes, Oleanane
D011753	Pyrones	Keto-pyrans.
D005960	Glucosides	A GLYCOSIDE that is derived from GLUCOSE.	Glucoside
D012855	Sitosterols	A family of sterols commonly found in plants and plant oils. Alpha-, beta-, and gamma-isomers have been characterized.
D047310	Apigenin	5,7,4'-trihydroxy-flavone, one of the FLAVONES.
D047311	Luteolin	5,7,3',4'-tetrahydroxy-flavone, one of the FLAVONES.	3',4',5,7-Tetrahydroxy-Flavone,3',4',5,7-Tetrahydroxyflavone,Luteoline
D057888	Iridoid Glucosides	A subclass of iridoid compounds that include a glucoside moiety, usually found at the C-1 position.	Iridoid Glucoside,Iridoidglucoside,Secoiridoid Glucoside,Iridoidglucosides,Secoiridoid Glucosides,Glucoside, Iridoid,Glucoside, Secoiridoid,Glucosides, Iridoid,Glucosides, Secoiridoid
D021241	Spectrometry, Mass, Electrospray Ionization	A mass spectrometry technique used for analysis of nonvolatile compounds such as proteins and macromolecules. The technique involves preparing electrically charged droplets from analyte molecules dissolved in solvent. The electrically charged droplets enter a vacuum chamber where the solvent is evaporated. Evaporation of solvent reduces the droplet size, thereby increasing the coulombic repulsion within the droplet. As the charged droplets get smaller, the excess charge within them causes them to disintegrate and release analyte molecules. The volatilized analyte molecules are then analyzed by mass spectrometry.	ESI Mass Spectrometry,Electrospray Ionization Mass Spectrometry,Mass Spectrometry, ESI,Spectrometry, ESI Mass
D029967	Swertia	A plant genus of the family GENTIANACEAE. It is a source of swertiapuniside and IRIDOID GLYCOSIDES.	Swertia chirata,Swertia chirayita,Swertias