[Nodular amyloidoma associated with primary pulmonary Malt lymphoma]. 2008

M Hourseau, and J Virally, and E Habib, and B Juberthie, and L Bienvenu
Service d'Anatomie et Cytologie Pathologiques, Hôpital Robert Ballanger, Aulnay sous Bois, France. dropetmur@free.fr

BACKGROUND Pulmonary amyloïdoma is a nodular formation containing amyloid deposits, which can mimick a pulmonary carcinoma. Its etiologic diagnosis require the search of an underlying infectious disease, a connective tissue disorder or a lymphoma. METHODS We report the case of a 73 year old woman, asymptomatic, presenting an incidental pulmonary opacity in the left upper lobe, associated with hilar lymphadenopathies, positive on PET scan. The patient underwent a left superior lobectomy with mediastinal lymphadenectomy. Histologically, the nodule was composed of amylodosis deposits. It was surrounded by a dense lymphoïd infiltrate. The phenotype (CD20+, CD5-, CD3-, CD23-) of the lymphoïd cells, like the demonstration of a lambda light chain restriction permited to pose the diagnostic of pulmonary Malt lymphoma and to characterize the AL lambda type of the amyloïdosis CONCLUSIONS Association of amyloïdoma and Malt lymphoma is a rare condition. The histologic diagnosis of lymphoma may be difficult in this case, the lymphomatous process being concealed by the volume of the amyloïd mass. Therefore it is necessary in case of amyloïdoma to search histological signs of Malt lymphoma and to confirm diagnosis by demonstrating a B clonality and a immunoglobulin light chains restriction.

UI MeSH Term Description Entries
D008175 Lung Neoplasms Tumors or cancer of the LUNG. Cancer of Lung,Lung Cancer,Pulmonary Cancer,Pulmonary Neoplasms,Cancer of the Lung,Neoplasms, Lung,Neoplasms, Pulmonary,Cancer, Lung,Cancer, Pulmonary,Cancers, Lung,Cancers, Pulmonary,Lung Cancers,Lung Neoplasm,Neoplasm, Lung,Neoplasm, Pulmonary,Pulmonary Cancers,Pulmonary Neoplasm
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D000686 Amyloidosis A group of sporadic, familial and/or inherited, degenerative, and infectious disease processes, linked by the common theme of abnormal protein folding and deposition of AMYLOID. As the amyloid deposits enlarge they displace normal tissue structures, causing disruption of function. Various signs and symptoms depend on the location and size of the deposits. Amyloidoses
D018442 Lymphoma, B-Cell, Marginal Zone Extranodal lymphoma of lymphoid tissue associated with mucosa that is in contact with exogenous antigens. Many of the sites of these lymphomas, such as the stomach, salivary gland, and thyroid, are normally devoid of lymphoid tissue. They acquire mucosa-associated lymphoid tissue (MALT) type as a result of an immunologically mediated disorder. Lymphoma, Mucosa-Associated Lymphoid Tissue,MALT Lymphoma,Marginal Zone B-Cell Lymphoma,Lymphoma of Mucosa-Associated Lymphoid Tissue,Mucosa-Associated Lymphoid Tissue Lymphoma,Lymphoma of Mucosa Associated Lymphoid Tissue,Lymphoma, MALT,Lymphoma, Mucosa Associated Lymphoid Tissue,Lymphomas, MALT,MALT Lymphomas,Marginal Zone B Cell Lymphoma,Mucosa Associated Lymphoid Tissue Lymphoma

Related Publications

M Hourseau, and J Virally, and E Habib, and B Juberthie, and L Bienvenu
September 2000, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc,
M Hourseau, and J Virally, and E Habib, and B Juberthie, and L Bienvenu
July 2017, Journal of community hospital internal medicine perspectives,
M Hourseau, and J Virally, and E Habib, and B Juberthie, and L Bienvenu
September 2007, The European respiratory journal,
M Hourseau, and J Virally, and E Habib, and B Juberthie, and L Bienvenu
July 1996, Histopathology,
M Hourseau, and J Virally, and E Habib, and B Juberthie, and L Bienvenu
January 2022, Respiratory medicine case reports,
M Hourseau, and J Virally, and E Habib, and B Juberthie, and L Bienvenu
November 2017, Internal medicine (Tokyo, Japan),
M Hourseau, and J Virally, and E Habib, and B Juberthie, and L Bienvenu
January 2010, Leukemia research,
M Hourseau, and J Virally, and E Habib, and B Juberthie, and L Bienvenu
March 2024, BMJ case reports,
M Hourseau, and J Virally, and E Habib, and B Juberthie, and L Bienvenu
February 2005, [Rinsho ketsueki] The Japanese journal of clinical hematology,
M Hourseau, and J Virally, and E Habib, and B Juberthie, and L Bienvenu
October 2007, La Revue du praticien,
Copied contents to your clipboard!