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Several risk factors for deep venous thrombosis (DVT) have been identified, and inherited thrombophilias constitute a significant proportion of them. The most common inherited thrombophilia is activated protein C (APC) resistance, and factor V Leiden is the most common cause of APC resistance. The high prevalence of APC resistance in Caucasians is established, and the prevalence among persons of Asian and African descent has been shown to be low in previous studies. Twenty-three patients with lower limb DVT were included in the study. Diagnosis was confirmed by duplex ultrasonography. Patients were tested for APC resistance with use of the STA Staclot APC-R system (Diagnostica Stago, Asnieres, France), as per the manufacturer's guidelines. Ten patients (43.5%) tested positive for APC resistance, while 13 (56.5%) tested negative. APC resistance, although considered a rarity, has been found to have a high prevalence in patients with DVT from the northeastern region of India. APC resistance estimation should be done for all patients with DVT.
Nikhil Agrawal, and
Sanjeev Kumar, and
Puneet, and
R Khanna, and
Jyoti Shukla, and
A K Khanna
September 2002,
Ceska gynekologie,
Nikhil Agrawal, and
Sanjeev Kumar, and
Puneet, and
R Khanna, and
Jyoti Shukla, and
A K Khanna
February 1994,
Lancet (London, England),
Nikhil Agrawal, and
Sanjeev Kumar, and
Puneet, and
R Khanna, and
Jyoti Shukla, and
A K Khanna
February 1994,
Lancet (London, England),
Nikhil Agrawal, and
Sanjeev Kumar, and
Puneet, and
R Khanna, and
Jyoti Shukla, and
A K Khanna
October 1996,
Journal of neurology,
Nikhil Agrawal, and
Sanjeev Kumar, and
Puneet, and
R Khanna, and
Jyoti Shukla, and
A K Khanna
October 1996,
Stroke,
Nikhil Agrawal, and
Sanjeev Kumar, and
Puneet, and
R Khanna, and
Jyoti Shukla, and
A K Khanna
July 1997,
Aviation, space, and environmental medicine,
Nikhil Agrawal, and
Sanjeev Kumar, and
Puneet, and
R Khanna, and
Jyoti Shukla, and
A K Khanna
June 1998,
Clinical pediatrics,
Nikhil Agrawal, and
Sanjeev Kumar, and
Puneet, and
R Khanna, and
Jyoti Shukla, and
A K Khanna
June 1996,
Archives des maladies du coeur et des vaisseaux,
Nikhil Agrawal, and
Sanjeev Kumar, and
Puneet, and
R Khanna, and
Jyoti Shukla, and
A K Khanna
October 1995,
The Journal of pediatrics,
Nikhil Agrawal, and
Sanjeev Kumar, and
Puneet, and
R Khanna, and
Jyoti Shukla, and
A K Khanna
November 1996,
The American journal of medicine,
