Biomaterial Database

Transcutaneous oxygen tension measurements in the assessment of limb ischaemia. 1991

F G Quigley, and I B Faris

University Department of Surgery, Royal Adelaide Hospital, Australia.

The measurement of transcutaneous oxygen tension (TcPO2) has been adapted for the assessment of the blood supply of the lower limb. This study was undertaken to determine the most useful means of expressing TcPO2 measurements. We studied 176 patients with peripheral vascular disease and/or diabetes and 34 normal volunteers. Approximately++ half of the patients studied had ulceration or gangrene of the foot. A comparison of three methods of expressing TcPO2 measurement for predicting presence of ulceration was made using ROCA analysis. The absolute value of TcPO2 on the dorsum of the foot was the best predictor of the presence of ulceration or gangrene. An absolute value of TcPO2 of 30 mmHg on the dorsum of the foot had a sensitivity of 42% and specificity of 91%. The sensitivity of the test was as good in diabetic patients as in non-diabetic patients.

UI	MeSH Term	Description	Entries
D007511	Ischemia	A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.	Ischemias
D007871	Leg Ulcer	Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.	Leg Ulcers,Ulcer, Leg,Ulcers, Leg
D010100	Oxygen	An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.	Dioxygen,Oxygen-16,Oxygen 16
D001785	Blood Gas Monitoring, Transcutaneous	The noninvasive measurement or determination of the partial pressure (tension) of oxygen and/or carbon dioxide locally in the capillaries of a tissue by the application to the skin of a special set of electrodes. These electrodes contain photoelectric sensors capable of picking up the specific wavelengths of radiation emitted by oxygenated versus reduced hemoglobin.	Carbon Dioxide Partial Pressure Determination, Transcutaneous,Cutaneous Oximetry,Oximetry, Transcutaneous,Oxygen Partial Pressure Determination, Transcutaneous,Transcutaneous Blood Gas Monitoring,Transcutaneous Capnometry,Transcutaneous Oximetry,PtcO2,TcPCO2,Capnometries, Transcutaneous,Capnometry, Transcutaneous,Cutaneous Oximetries,Oximetries, Cutaneous,Oximetries, Transcutaneous,Oximetry, Cutaneous,Transcutaneous Capnometries,Transcutaneous Oximetries
D003920	Diabetes Mellitus	A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
D005121	Extremities	The farthest or outermost projections of the body, such as the HAND and FOOT.	Limbs,Extremity,Limb
D005734	Gangrene	Death and putrefaction of tissue usually due to a loss of blood supply.	Gangrenes
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014652	Vascular Diseases	Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.	Disease, Vascular,Diseases, Vascular,Vascular Disease
D015994	Incidence	The number of new cases of a given disease during a given period in a specified population. It also is used for the rate at which new events occur in a defined population. It is differentiated from PREVALENCE, which refers to all cases in the population at a given time.	Attack Rate,Cumulative Incidence,Incidence Proportion,Incidence Rate,Person-time Rate,Secondary Attack Rate,Attack Rate, Secondary,Attack Rates,Cumulative Incidences,Incidence Proportions,Incidence Rates,Incidence, Cumulative,Incidences,Person time Rate,Person-time Rates,Proportion, Incidence,Rate, Attack,Rate, Incidence,Rate, Person-time,Rate, Secondary Attack,Secondary Attack Rates