-transparent.png){kind=logo}
The humoral antibody response of feline leukemia virus (FeLV)-exposed cats to the feline oncornavirus-associated tumor cell-membrane antigen (FOCMA) is directly correlated with immunosurveillance against tumor development under natural conditions. By means of membrane immunofluorescence and radioimmunoprecipitation, the antibody response to FOCMA was found to be independent of the antibody response to the major envelope and core proteins of FeLV, gp70 and p30. This was especially true for healthy viremic cats, where antigenemia with circulating FeLV gp70 and p30 apparently binds any free antibody to these proteins, but high levels of FOCMA antibody are often concurrently present. Exhaustive in vitro absorption of highly immune nonviremic serum with gp70 and p30 also failed to remove FOCMA antibody activity. These results indicate that FOCMA is not one of these major FeLV structural proteins.
J R Stephenson, and
M Essex, and
S Hino, and
W D Hardy, and
S A Aaronson
January 1979,
Journal of immunological methods,
J R Stephenson, and
M Essex, and
S Hino, and
W D Hardy, and
S A Aaronson
December 1983,
Virology,
J R Stephenson, and
M Essex, and
S Hino, and
W D Hardy, and
S A Aaronson
March 1978,
Proceedings of the National Academy of Sciences of the United States of America,
J R Stephenson, and
M Essex, and
S Hino, and
W D Hardy, and
S A Aaronson
March 1977,
Journal of the National Cancer Institute,
J R Stephenson, and
M Essex, and
S Hino, and
W D Hardy, and
S A Aaronson
November 1971,
International journal of cancer,
J R Stephenson, and
M Essex, and
S Hino, and
W D Hardy, and
S A Aaronson
August 1972,
Nature: New biology,
J R Stephenson, and
M Essex, and
S Hino, and
W D Hardy, and
S A Aaronson
January 1980,
Cold Spring Harbor symposia on quantitative biology,
J R Stephenson, and
M Essex, and
S Hino, and
W D Hardy, and
S A Aaronson
June 1977,
Science (New York, N.Y.),
J R Stephenson, and
M Essex, and
S Hino, and
W D Hardy, and
S A Aaronson
January 1981,
Haematology and blood transfusion,
J R Stephenson, and
M Essex, and
S Hino, and
W D Hardy, and
S A Aaronson
June 1976,
Journal of the National Cancer Institute,
