Biomaterial Database

[Fundamental and applied objectives of investigations in immersion]. 2008

I B Kozlovskaia

The results of extended comparative investigations into the hypogravity effects on the human motor system in space flight and ground-based experiments evidenced that dry immersions (DI) is the most adequate model of microgravity as time of development, degree and depth of structural and functional motor disorders in DI are very close to what is observed in real microgravity. High intensity and speed of the hypogravity effects during immersion as compared with bed rest hypokinesia the only difference from which is the level of support removal provided insight into the leading (trigger) role of support removal in genesis of the microgravity-induced syndromes of muscular deconditioning and hypogravitational ataxia. Involvement and paths of support afferentation within the muscular system were experimentally studied and verified. Much less understood are processes changing the system mechanisms. These issues as well as some nontrivial approaches to elimination of the negative effects of hypogravity were the subject of the multisided immersion experiment the results of which are presented in this book of the journal.

UI	MeSH Term	Description	Entries
D007101	Immersion	The placing of a body or a part thereof into a liquid.	Submersion,Immersions,Submersions
D011379	Prognosis	A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.	Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001259	Ataxia	Impairment of the ability to perform smoothly coordinated voluntary movements. This condition may affect the limbs, trunk, eyes, pharynx, larynx, and other structures. Ataxia may result from impaired sensory or motor function. Sensory ataxia may result from posterior column injury or PERIPHERAL NERVE DISEASES. Motor ataxia may be associated with CEREBELLAR DISEASES; CEREBRAL CORTEX diseases; THALAMIC DISEASES; BASAL GANGLIA DISEASES; injury to the RED NUCLEUS; and other conditions.	Coordination Impairment,Dyssynergia,Incoordination,Ataxia, Appendicular,Ataxia, Limb,Ataxia, Motor,Ataxia, Sensory,Ataxia, Truncal,Ataxy,Dyscoordination,Lack of Coordination,Tremor, Rubral,Appendicular Ataxia,Appendicular Ataxias,Ataxias,Ataxias, Appendicular,Ataxias, Limb,Ataxias, Motor,Ataxias, Sensory,Ataxias, Truncal,Coordination Impairments,Coordination Lack,Impairment, Coordination,Impairments, Coordination,Incoordinations,Limb Ataxia,Limb Ataxias,Motor Ataxia,Motor Ataxias,Rubral Tremor,Rubral Tremors,Sensory Ataxia,Sensory Ataxias,Tremors, Rubral,Truncal Ataxia,Truncal Ataxias
D018474	Weightlessness Simulation	Condition under normal Earth gravity where the force of gravity itself is not actually altered but its influence or effect may be modified and studied. (From ASGSB Bull 1992;5(2):27)	Microgravity Simulation,Models, Weightlessness,Simulation, Microgravity,Simulation, Weightlessness,Weightlessness Model,Weightlessness Models
D018476	Hypokinesia	Slow or diminished movement of body musculature. It may be associated with BASAL GANGLIA DISEASES; MENTAL DISORDERS; prolonged inactivity due to illness; and other conditions.	Bradykinesia,Hypodynamia,Hypokinesia, Antiorthostatic,Antiorthostatic Hypokinesia,Antiorthostatic Hypokinesias,Bradykinesias,Hypokinesias, Antiorthostatic