Pachydermoperiostosis: technetium-99m-methylene diphosphonate scintigraphic pattern. 1991

J Bomanji, and N Nagaraj, and R Jewkes, and M Fields, and R N Maini
Department of Nuclear Medicine, St. Bartholomew's Hospital, London, United Kingdom.

We present two cases of pachydermoperiostosis. Both patients presented with joint pains and swelling. Bone scan revealed marked pericortical uptake involving the distal end of long bones. The distribution pattern and differential diagnosis of the scan abnormalities are discussed.

UI MeSH Term Description Entries
D008297 Male Males
D010004 Osteoarthropathy, Primary Hypertrophic A condition chiefly characterized by thickening of the skin of the head and distal extremities, deep folds and furrows of the skin of the forehead, cheeks, and scalp, SEBORRHEA; HYPERHIDROSIS; periostosis of the long bones, digital clubbing, and spadelike enlargement of the hands and feet. It is more prevalent in the male, and is usually first evident during adolescence. Inheritance is primarily autosomal recessive, but an autosomal dominant form exists. Pachydermoperiostosis,Acropachy, Hereditary,Clubbing of Digits,Cranioosteoarthropathy,Currarino Idiopathic Osteoarthropathy,Digital Clubbing, Isolated Congenital,Familial Idiopathic Osteoarthropathy Of Childhood,Hypertrophic Osteoarthropathy, Primary, Autosomal Dominant,Hypertrophic Osteoarthropathy, Primary, Autosomal Recessive,Idiopathic Hypertrophic Osteoarthropathy,Pachydermoperiostosis, Autosomal Dominant,Pachydermoperiostosis, Autosomal Recessive,Primary Hypertrophic Osteoarthropathy, Autosomal Dominant,Touraine-Solente-Gole Syndrome,Acropachies, Hereditary,Autosomal Dominant Pachydermoperiostoses,Autosomal Dominant Pachydermoperiostosis,Autosomal Recessive Pachydermoperiostosis,Cranioosteoarthropathies,Hereditary Acropachies,Hereditary Acropachy,Hypertrophic Osteoarthropathy, Idiopathic,Hypertrophic Osteoarthropathy, Primary,Osteoarthropathy, Currarino Idiopathic,Osteoarthropathy, Idiopathic Hypertrophic,Pachydermoperiostoses, Autosomal Dominant,Primary Hypertrophic Osteoarthropathy,Recessive Pachydermoperiostosis, Autosomal,Touraine Solente Gole Syndrome
D011877 Radionuclide Imaging The production of an image obtained by cameras that detect the radioactive emissions of an injected radionuclide as it has distributed differentially throughout tissues in the body. The image obtained from a moving detector is called a scan, while the image obtained from a stationary camera device is called a scintiphotograph. Gamma Camera Imaging,Radioisotope Scanning,Scanning, Radioisotope,Scintigraphy,Scintiphotography,Imaging, Gamma Camera,Imaging, Radionuclide
D001842 Bone and Bones A specialized CONNECTIVE TISSUE that is the main constituent of the SKELETON. The principal cellular component of bone is comprised of OSTEOBLASTS; OSTEOCYTES; and OSTEOCLASTS, while FIBRILLAR COLLAGENS and hydroxyapatite crystals form the BONE MATRIX. Bone Tissue,Bone and Bone,Bone,Bones,Bones and Bone,Bones and Bone Tissue,Bony Apophyses,Bony Apophysis,Condyle,Apophyses, Bony,Apophysis, Bony,Bone Tissues,Condyles,Tissue, Bone,Tissues, Bone
D003937 Diagnosis, Differential Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures. Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D013669 Technetium Tc 99m Medronate A gamma-emitting radionuclide imaging agent used primarily in skeletal scintigraphy. Because of its absorption by a variety of tumors, it is useful for the detection of neoplasms. Tc-99m MDP,Technetium Methylene Diphosphonate,99mTc-MDP,99mTc-Methylene Diphosphonate,Tc-99 Medronate,Tc-99m Methylene Diphosphonate,Technetium Tc 99m Methylenediphosphonate,99mTc Methylene Diphosphonate,Diphosphonate, 99mTc-Methylene,Diphosphonate, Tc-99m Methylene,Diphosphonate, Technetium Methylene,Medronate, Tc-99,Methylene Diphosphonate, Tc-99m,Methylene Diphosphonate, Technetium,Tc 99 Medronate,Tc 99m Methylene Diphosphonate

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