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ET 495 and apomorphine, injected in small doses (0.1--1 microng/kg) into the femoral artery, induced a dose-dependent increase in femoral blood flow. This dilator effect was abolished by section of the ipsilateral femoral nerve and sciatic nerve, transection of the spinal cord, alpha-adrenoceptor blockade, ganglionic blockade and guanethidine. In addition, the increase in blood flow was inhibited by intravenous administration of haloperiol (2 mg/kg i.v.) or pimozide (2 mg/kg i.v.) and by injection of small doses (10--50 microng/kg) of these drugs into the femoral artery. It was concluded that a dopaminergic component located in the femoral vascular bed of the dog may be involved in the local vasodilator and sympathoinhibitory effect of apomorphine and ET 495.
M Laubie, and
H Schmitt, and
E Falq
January 1977,
Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie,
M Laubie, and
H Schmitt, and
E Falq
April 1965,
Circulation research,
M Laubie, and
H Schmitt, and
E Falq
February 1985,
European journal of pharmacology,
M Laubie, and
H Schmitt, and
E Falq
November 1974,
Acta pharmacologica et toxicologica,
M Laubie, and
H Schmitt, and
E Falq
December 1980,
The Journal of pharmacology and experimental therapeutics,
M Laubie, and
H Schmitt, and
E Falq
January 1977,
Advances in biochemical psychopharmacology,
M Laubie, and
H Schmitt, and
E Falq
November 1972,
British journal of pharmacology,
M Laubie, and
H Schmitt, and
E Falq
October 1977,
European journal of pharmacology,
M Laubie, and
H Schmitt, and
E Falq
July 1960,
UCRL [reports]. U.S. Atomic Energy Commission,
M Laubie, and
H Schmitt, and
E Falq
January 1978,
Advances in biochemical psychopharmacology,
