Biomaterial Database

Case report: fatal pulmonary toxoplasmosis following chemotherapy. 1991

N J Brown, and S McKenzie, and M D Decker

Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232.

A 41-year-old woman with acute myelomonocytic leukemia in remission died of a rapidly progressive necrotizing pneumonia while in the recovery phase following consolidation chemotherapy. Autopsy revealed disseminated toxoplasmosis. Although this syndrome has been well described to present as a neurologic complication in certain immunocompromised patients, it is rare in acute leukemia, and non-neurologic presentations are even more unusual. This case emphasizes the need to be suspicious of toxoplasmosis in immunocompromised patients even in the absence of neurologic signs or symptoms.

UI	MeSH Term	Description	Entries
D008174	Lung Diseases, Parasitic	Infections of the lungs with parasites, most commonly by parasitic worms (HELMINTHS).	Parasitic Lung Diseases,Parasitic Infections of Lung,Pulmonary Parasitic Infections,Lung Disease, Parasitic,Lung Parasitic Infection,Lung Parasitic Infections,Parasitic Infection, Pulmonary,Parasitic Infections, Pulmonary,Parasitic Lung Disease,Pulmonary Parasitic Infection
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D014123	Toxoplasmosis	The acquired form of infection by Toxoplasma gondii in animals and man.	Toxoplasma gondii Infection,Infection, Toxoplasma gondii
D015479	Leukemia, Myelomonocytic, Acute	A pediatric acute myeloid leukemia involving both myeloid and monocytoid precursors. At least 20% of non-erythroid cells are of monocytic origin.	Leukemia, Myeloid, Acute, M4,Leukemia, Myeloid, Naegeli-Type,Myeloid Leukemia, Acute, M4,Myeloid Leukemia, Naegeli-Type,Myelomonocytic Leukemia, Acute,Acute Myelomonocytic Leukemia,Acute Myelomonocytic Leukemias,Leukemia, Acute Myelomonocytic,Leukemia, Naegeli-Type Myeloid,Leukemias, Acute Myelomonocytic,Myeloid Leukemia, Naegeli Type,Myelomonocytic Leukemias, Acute,Naegeli-Type Myeloid Leukemia
D016867	Immunocompromised Host	A human or animal whose immunologic mechanism is deficient because of an immunodeficiency disorder or other disease or as the result of the administration of immunosuppressive drugs or radiation.	Immunosuppressed Host,Immunocompromised Patient,Host, Immunocompromised,Host, Immunosuppressed,Hosts, Immunocompromised,Hosts, Immunosuppressed,Immunocompromised Hosts,Immunocompromised Patients,Immunosuppressed Hosts,Patient, Immunocompromised,Patients, Immunocompromised