BIOMAT Database Logo BIOMAT Database Logo

Extracorporeal circulation in the management of massive propranolol overdose. 1991

F K McVey, and C F Corke
Sir Humphry Davy Department of Anaesthesia, Bristol.

A case of refractory hypotension following propranolol overdose is reported. Management included isoprenaline, glucagon and extracorporeal circulatory support using femoral vein-femoral artery bypass. The unreliability of neurological observations, especially unreactive pupils, in the presence of drug overdose is reiterated.

UI MeSH Term Description Entries
D007022 Hypotension Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients. Blood Pressure, Low,Hypotension, Vascular,Low Blood Pressure,Vascular Hypotension
D011433 Propranolol A widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs. Dexpropranolol,AY-20694,Anaprilin,Anapriline,Avlocardyl,Betadren,Dociton,Inderal,Obsidan,Obzidan,Propanolol,Propranolol Hydrochloride,Rexigen,AY 20694,AY20694,Hydrochloride, Propranolol
D005112 Extracorporeal Circulation Diversion of blood flow through a circuit located outside the body but continuous with the bodily circulation. Circulation, Extracorporeal,Circulations, Extracorporeal,Extracorporeal Circulations
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D013406 Suicide, Attempted The unsuccessful attempt to kill oneself. Parasuicide,Suicide Attempt,Attempt, Suicide,Attempted Suicide,Parasuicides
D062787 Drug Overdose Accidental or deliberate use of a medication or street drug in excess of normal dosage. Drug Overdoses,Overdose, Drug,Overdoses, Drug

Related Publications

F K McVey, and C F Corke
Massive propranolol overdose.
December 1986, The American journal of medicine,
F K McVey, and C F Corke
Extracorporeal circulation in the management of severe tricyclic antidepressant overdose.
July 1994, The American journal of emergency medicine,
F K McVey, and C F Corke
Venoarterial extracorporeal membrane oxygenation for the management of massive amlodipine overdose.
January 2014, Perfusion,
F K McVey, and C F Corke
Massive hemolysis in extracorporeal circulation.
March 1961, The Journal of thoracic and cardiovascular surgery,
F K McVey, and C F Corke
Use of extracorporeal membrane oxygenation in massive amlodipine overdose.
December 2022, Archives of toxicology,
F K McVey, and C F Corke
Management of massive verapamil overdose.
July 1991, The Medical journal of Australia,
F K McVey, and C F Corke
Management of massive verapamil overdose.
November 1991, The Medical journal of Australia,
F K McVey, and C F Corke
Massive diltiazem overdose treated with extracorporeal membrane oxygenation.
July 2003, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies,
F K McVey, and C F Corke
Propranolol overdose.
March 1992, Anaesthesia,
F K McVey, and C F Corke
Propranolol overdose.
January 1980, Annals of emergency medicine,
Copied contents to your clipboard!