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Steroidal constituents from the aerial parts of Lippia nodiflora Linn. 2009

Bina S Siddiqui, and Fayaz Ahmed, and S Kashif Ali, and Sobiya Perwaiz, and Sabira Begum
International Centre for Chemical Sciences, HEJ Research institute of Chemistry and Dr Panjwani Center for Molecular Medicine and Drug Research, Karachi, Pakistan. bina@khi.comsats.net.pk

The methanolic extract of the aerial parts of Lippia nodiflora Linn. afforded one new and two known steroids. The structure of the new steroid had been elucidated as 4',5'-dimethoxybenzoloxystigmasterol (1) by an analysis of the spectral data, including extensive NMR experiments and its chemical transformation to stigmasterol. The known steroids were identified as stigmasterol and beta-sitosterol through comparison of their spectral data with those reported in the literature.

UI MeSH Term Description Entries
D013256 Steroids A group of polycyclic compounds closely related biochemically to TERPENES. They include cholesterol, numerous hormones, precursors of certain vitamins, bile acids, alcohols (STEROLS), and certain natural drugs and poisons. Steroids have a common nucleus, a fused, reduced 17-carbon atom ring system, cyclopentanoperhydrophenanthrene. Most steroids also have two methyl groups and an aliphatic side-chain attached to the nucleus. (From Hawley's Condensed Chemical Dictionary, 11th ed) Steroid,Catatoxic Steroids,Steroids, Catatoxic
D013265 Stigmasterol Poriferasterol
D015394 Molecular Structure The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds. Structure, Molecular,Molecular Structures,Structures, Molecular
D032411 Lippia A plant genus of the family VERBENACEAE. Lippsidoquinone; TRITERPENES; SESQUITERPENES; and THYMOL have been found in this genus. Plant extracts have cytotoxic activity. It is sometimes called Mexican oregano but that confuses it with real oregano (ORIGANUM). Lippias
D035261 Plant Components, Aerial The above-ground plant without the roots. Aerial Parts, Plant,Aerial Plant Components,Aerial Part, Plant,Aerial Plant Component,Component, Aerial Plant,Components, Aerial Plant,Part, Plant Aerial,Parts, Plant Aerial,Plant Aerial Part,Plant Aerial Parts,Plant Component, Aerial

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