Histological changes in human dental pulp following application of intrusive and extrusive orthodontic forces. 2009

Barat A Ramazanzadeh, and Abbas A Sahhafian, and Nooshin Mohtasham, and Nadia Hassanzadeh, and Arezoo Jahanbin, and Mohammad T Shakeri
Department of Orthodontics, Faculty of Dentistry and Dental School Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

The aim of this study was to compare the effects of orthodontic extrusive and intrusive forces on histological changes of the human dental pulp. In this clinical trial, 52 sound upper first premolars from 26 patients scheduled for extraction for orthodontic reasons were selected. They were divided into 2 groups, based on the time intervals for histological evaluation (3 days and 3 weeks). In each group, 10 teeth received orthodontic extrusive forces, 10 teeth underwent intrusive forces, and 6 teeth served as controls. After each period, teeth were extracted and prepared for histological examination under light microscopy and some histological parameters were evaluated. The data were statistically analyzed by Kruskall-Wallis and Mann Whitney tests. Of the parameters evaluated, just vacuolization and disruption of the odontoblastic layer showed statistically significant differences between the control group and both of the experimental groups in each test period (P < 0.05). Additionally, there was no significant difference between 3-day and 3-week intervals in each experimental group, except for fibrosis in the extrusive group which significantly increased after 3 weeks of force application (P = 0.001). Histological pulp changes following extrusive and intrusive force applications for 3 days and 3 weeks show no difference from each other.

UI MeSH Term Description Entries
D008297 Male Males
D009804 Odontoblasts The mesenchymal cells which line the DENTAL PULP CAVITY and produce DENTIN. They have a columnar morphology in the coronal pulp but are cuboidal in the root pulp, or when adjacent to tertiary dentin. Odontoblast
D011671 Pulpitis Inflammation of the DENTAL PULP, usually due to bacterial infection in dental caries, tooth fracture, or other conditions causing exposure of the pulp to bacterial invasion. Chemical irritants, thermal factors, hyperemic changes, and other factors may also cause pulpitis. Inflammation, Endodontic,Endodontic Inflammation,Endodontic Inflammations,Inflammations, Endodontic,Pulpitides
D003739 Dental Cementum The bonelike rigid connective tissue covering the root of a tooth from the cementoenamel junction to the apex and lining the apex of the root canal, also assisting in tooth support by serving as attachment structures for the periodontal ligament. (Jablonski, Dictionary of Dentistry, 1992) Cementoblasts,Cementum,Cementoblast,Cementum, Dental
D003782 Dental Pulp A richly vascularized and innervated connective tissue of mesodermal origin, contained in the central cavity of a tooth and delimited by the dentin, and having formative, nutritive, sensory, and protective functions. (Jablonski, Dictionary of Dentistry, 1992) Dental Pulps,Pulp, Dental,Pulps, Dental
D003784 Dental Pulp Calcification CALCINOSIS of the DENTAL PULP or ROOT CANAL. Dental Pulp Stones,Denticle,Anomalous Dysplasia of Dentin,Calcification, Dental Pulp,Coronal Dentin Dysplasia,Dental Pulp Stone,Denticles,Dentin Dyspalsia, Shields Type 2,Dentin Dysplasia, Coronal,Dentin Dysplasia, Shields Type II,Dentin Dysplasia, Type II,Pulp Calcification, Dental,Pulp Stone, Dental,Pulp Stones,Pulp Stones, Dental,Pulpal Dysplasia,Stone, Dental Pulp,Stones, Dental Pulp,Calcifications, Dental Pulp,Coronal Dentin Dysplasias,Dental Pulp Calcifications,Dentin Anomalous Dysplasia,Dentin Anomalous Dysplasias,Dentin Dysplasias, Coronal,Dysplasia, Coronal Dentin,Dysplasia, Pulpal,Dysplasias, Coronal Dentin,Dysplasias, Pulpal,Pulp Calcifications, Dental,Pulp Stone,Pulpal Dysplasias,Stone, Pulp,Stones, Pulp
D003790 Dental Pulp Necrosis Death of pulp tissue with or without bacterial invasion. When the necrosis is due to ischemia with superimposed bacterial infection, it is referred to as pulp gangrene. When the necrosis is non-bacterial in origin, it is called pulp mummification. Dental Pulp Autolysis,Dental Pulp Gangrene,Necrosis, Dental Pulp,Pulp Gangrene,Pulp Mummification,Pulp Necrosis,Autolysis, Dental Pulp,Gangrene, Dental Pulp,Necroses, Pulp,Pulp Autolysis, Dental,Pulp Gangrene, Dental,Pulp Necroses,Pulp Necrosis, Dental,Autolyses, Dental Pulp,Dental Pulp Autolyses,Dental Pulp Necroses,Gangrene, Pulp,Gangrenes, Pulp,Mummification, Pulp,Mummifications, Pulp,Necroses, Dental Pulp,Necrosis, Pulp,Pulp Autolyses, Dental,Pulp Gangrenes,Pulp Mummifications,Pulp Necroses, Dental
D003804 Dentin The hard portion of the tooth surrounding the pulp, covered by enamel on the crown and cementum on the root, which is harder and denser than bone but softer than enamel, and is thus readily abraded when left unprotected. (From Jablonski, Dictionary of Dentistry, 1992) Dentine,Dentines,Dentins
D003809 Dentin, Secondary Dentin formed by normal pulp after completion of root end formation. Secondary Dentin,Dentins, Secondary,Secondary Dentins
D004108 Dilatation, Pathologic The condition of an anatomical structure's being dilated beyond normal dimensions. Ectasia,Dilatation, Pathological,Dilatations, Pathologic,Dilatations, Pathological,Pathologic Dilatation,Pathologic Dilatations,Pathological Dilatation,Pathological Dilatations

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