Biomaterial Database

[On the biologic phenomenon of epidermotropism (author's transl)]. 1977

H Bardach

The biologic phenomenon of epidermotropism is mirrored in the dynamic equilibrium between different cell types within the epidermis. In various pathological conditions, this balance may be upset, or foreign epithelial, neuroectodermal and mesenchymal tissue may selectively infiltrate epidermal or other epithelial structures. The importance of the concept of epidermal symbiosis in these conditions and resulting similarities in the clinical picture and biologic behavior are pointed out.

UI	MeSH Term	Description	Entries
D009182	Mycosis Fungoides	A chronic, malignant T-cell lymphoma of the skin. In the late stages, the LYMPH NODES and viscera are affected.
D010144	Paget's Disease, Mammary	An intraductal in situ carcinoma of the breast, characterized clinically by eczema-like inflammatory skin changes and histologically by infiltration of the dermis by malignant cells (Paget's cells).	Paget's Disease of Breast,Mammary Paget Disease,Mammary Paget's Disease,Paget Disease of Breast,Paget Disease, Mammary,Paget's Disease of the Breast,Paget's Disease of the Nipple,Paget's Disease of the Nipple and Areola,Pigmented Mammary Paget Disease,Disease, Mammary Paget,Disease, Mammary Paget's,Mammary Pagets Disease,Paget Disease, Breast,Pagets Disease, Breast,Pagets Disease, Mammary
D010145	Paget Disease, Extramammary	A rare cutaneous neoplasm that occurs in the elderly. It develops more frequently in women and predominantly involves apocrine gland-bearing areas, especially the vulva, scrotum, and perianal areas. The lesions develop as erythematous scaly patches that progress to crusted, pruritic, erythematous plaques. The clinical differential diagnosis includes squamous cell carcinoma in situ and superficial fungal infection. It is generally thought to be an adenocarcinoma of the epidermis, from which it extends into the contiguous epithelium of hair follicles and eccrine sweat ducts. (DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1478)	Paget Disease Extramammary,Paget's Disease, Extramammary,Extra-Mammary Paget Disease,Extra-Mammary Paget's Disease,Extramammary Paget Disease,Extramammary Paget's Disease,Paget Disease, Extra-Mammary,Paget's Disease, Extra-Mammary,Extra Mammary Paget Disease,Extra Mammary Paget's Disease,Extra-Mammary Pagets Disease,Extramammary Pagets Disease,Extramammary, Paget Disease,Paget Disease, Extra Mammary,Paget's Disease, Extra Mammary,Pagets Disease, Extra-Mammary,Pagets Disease, Extramammary
D002465	Cell Movement	The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.	Cell Migration,Locomotion, Cell,Migration, Cell,Motility, Cell,Movement, Cell,Cell Locomotion,Cell Motility,Cell Movements,Movements, Cell
D002471	Cell Transformation, Neoplastic	Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.	Neoplastic Transformation, Cell,Neoplastic Cell Transformation,Transformation, Neoplastic Cell,Tumorigenic Transformation,Cell Neoplastic Transformation,Cell Neoplastic Transformations,Cell Transformations, Neoplastic,Neoplastic Cell Transformations,Neoplastic Transformations, Cell,Transformation, Cell Neoplastic,Transformation, Tumorigenic,Transformations, Cell Neoplastic,Transformations, Neoplastic Cell,Transformations, Tumorigenic,Tumorigenic Transformations
D005855	Germ Layers	The three primary germinal layers (ECTODERM; ENDODERM; and MESODERM) developed during GASTRULATION that provide tissues and body plan of a mature organism. They derive from two early layers, hypoblast and epiblast.	Epiblast,Hypoblast,Epiblasts,Germ Layer,Hypoblasts,Layer, Germ,Layers, Germ
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012867	Skin	The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS.
D012878	Skin Neoplasms	Tumors or cancer of the SKIN.	Cancer of Skin,Skin Cancer,Cancer of the Skin,Neoplasms, Skin,Cancer, Skin,Cancers, Skin,Neoplasm, Skin,Skin Cancers,Skin Neoplasm