The aim of the study was to assess the effect of amine fluoride (AmF)--stannous fluoride (SnF2) containing toothpaste and mouthrinsing on dental plaque accumulation and gingivitis. The examinations were performed on two groups of 20 (using AmF/SnF2)-, resp. 24 (using NaF) participants. The mean age was 45.6-, resp. 48.8 years. The duration of the study was five months. Toothbrushing was performed with standardized (multi-effect) toothbrushes, and after it mouthrinsing twice a day. Dental plaque was scored with the Plaque Index of Silness and Löe (1964) and gingivitis was assessed by the modified Sulcus Bleeding Index (Mühlemann and Son 1971) Plaque Index mean values showed a significant decreased in both groups (p less than 0.01). The reduction in the AmF/SnF2 group was more pronounced (63.7%) than in the NaF group (39.3%). The Sulcus-Bleeding Index mean values decreased also significantly in both groups (p less than 0.01). The decrease in the AmF/SnF2 group was 56.5% and in the NaF group 39.0%. CONCLUSIONS in the course of a five-month's period AmF/SnF2 containing toothpaste and mouthrinsing had better clinical effect on plaque accumulation and gingivitis than NaF containing toothpaste and mouthrinsing.