BIOMAT Database Logo BIOMAT Database Logo

Neonatal sensorineural hearing loss associated with furosemide: a case-control study. 1991

D R Brown, and J F Watchko, and D Sabo
Department of Pediatrics, University of Pittsburgh Medical School, PA.

Thirty-five neonates with sensorineural hearing loss (SNHL), identified by brainstem auditory evoked response (BAER), and 70 matched controls with normal BAERs were studied. All infants had had BAERs before discharge from hospital as part of a screening program for high-risk neonates. Infants with SNHL showed no response to a 60dBnHL click stimulus and all had these results confirmed on at least one occasion after hospital discharge. Based on the screening program results, over-all prevalence of non-hereditary hearing loss was estimated to be 0.93 per 1000 live births, and in neonates weighing less than 2000g at birth to be 15.54 per 1000 live births. Several factors, including seizures, exposure to anticonvulsant drugs, furosemide and kanamycin were associated with SNHL, but after multivariate analysis, only exposure to furosemide remained significant. Peak serum bilirubin concentration and benzyl alcohol exposure did not appear to be related to hearing loss.

UI MeSH Term Description Entries
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D007235 Infant, Premature, Diseases Diseases that occur in PREMATURE INFANTS.
D007363 Intensive Care Units, Neonatal Hospital units providing continuing surveillance and care to acutely ill newborn infants. Neonatal Intensive Care Unit,Neonatal Intensive Care Units,Newborn Intensive Care Unit,Newborn Intensive Care Units,ICU, Neonatal,Neonatal ICU,Newborn ICU,Newborn Intensive Care Units (NICU),ICU, Newborn,ICUs, Neonatal,ICUs, Newborn,Neonatal ICUs,Newborn ICUs
D008297 Male Males
D001933 Brain Stem The part of the brain that connects the CEREBRAL HEMISPHERES with the SPINAL CORD. It consists of the MESENCEPHALON; PONS; and MEDULLA OBLONGATA. Brainstem,Truncus Cerebri,Brain Stems,Brainstems,Cerebri, Truncus,Cerebrus, Truncus,Truncus Cerebrus
D002675 Child, Preschool A child between the ages of 2 and 5. Children, Preschool,Preschool Child,Preschool Children
D003638 Deafness A general term for the complete loss of the ability to hear from both ears. Deafness Permanent,Hearing Loss Permanent,Prelingual Deafness,Deaf Mutism,Deaf-Mutism,Deafness, Acquired,Hearing Loss, Complete,Hearing Loss, Extreme,Acquired Deafness,Complete Hearing Loss,Deafness, Prelingual,Extreme Hearing Loss,Permanent, Deafness,Permanent, Hearing Loss,Permanents, Deafness
D005260 Female Females
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D005665 Furosemide A benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for EDEMA and chronic RENAL INSUFFICIENCY. Frusemide,Fursemide,Errolon,Frusemid,Furanthril,Furantral,Furosemide Monohydrochloride,Furosemide Monosodium Salt,Fusid,Lasix

Related Publications

D R Brown, and J F Watchko, and D Sabo
Laboratory assessment of sudden sensorineural hearing loss: A case-control study.
October 2017, The Laryngoscope,
D R Brown, and J F Watchko, and D Sabo
Risk of sensorineural hearing loss with macrolide antibiotics: A nested case-control study.
January 2017, The Laryngoscope,
D R Brown, and J F Watchko, and D Sabo
Sensorineural hearing loss associated with ulcerative colitis. A case report.
December 1984, Archives of otolaryngology (Chicago, Ill. : 1960),
D R Brown, and J F Watchko, and D Sabo
Metabolic syndrome components and sudden sensorineural hearing loss: a case-control study.
April 2020, European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery,
D R Brown, and J F Watchko, and D Sabo
Cardiovascular Risk Factors and Sudden Sensorineural Hearing Loss: A Case-Control Study.
February 2023, Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology,
D R Brown, and J F Watchko, and D Sabo
Etiological analysis of patients with sudden sensorineural hearing loss: a prospective case-control study.
March 2023, Scientific reports,
D R Brown, and J F Watchko, and D Sabo
Neonatal ventilation and sensorineural hearing loss.
September 1995, Journal of the American Academy of Audiology,
D R Brown, and J F Watchko, and D Sabo
Sensorineural hearing loss associated with hypoparathyroidism.
September 1987, The Laryngoscope,
D R Brown, and J F Watchko, and D Sabo
Sensorineural hearing loss associated with firearms.
November 1969, Archives of otolaryngology (Chicago, Ill. : 1960),
D R Brown, and J F Watchko, and D Sabo
Seasonal sensorineural hearing loss associated with allergic rhinitis: a case report.
February 2006, The Journal of allergy and clinical immunology,
Copied contents to your clipboard!