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This prospective study compares the accuracy of barium enema examination performed by experienced radiologists to colonoscopy performed by experienced gastroenterologists blinded to the radiographic findings to detect proximal, synchronous lesions in patients with polyps detected during fiberoptic sigmoidoscopy. Three thousand six patients were examined, of whom 147 (5%) had polyps larger than 0.5 cm in diameter. Of 114 patients who completed the protocol, 46 patients (40%) had synchronous, proximal colonic lesions. There were no radiographic false positives, but the single-contrast barium enema missed polyps in 13 while detecting polyps in 2 patients (sensitivity = 13%). The double-contrast barium enema missed proximal polyps in 23 patients while detecting them in 8 (sensitivity = 26%). We conclude that patients with neoplastic polyps found during fiberoptic sigmoidoscopy should have colonoscopy without barium enema. If the entire colon cannot be examined at colonoscopy, we advise double-contrast barium enema.
R G Norfleet, and
M E Ryan, and
J B Wyman, and
R A Rhodes, and
J F Nunez, and
J P Kirchner, and
K Parent
April 1990,
Gastroenterology,
R G Norfleet, and
M E Ryan, and
J B Wyman, and
R A Rhodes, and
J F Nunez, and
J P Kirchner, and
K Parent
August 1995,
Gastrointestinal endoscopy,
R G Norfleet, and
M E Ryan, and
J B Wyman, and
R A Rhodes, and
J F Nunez, and
J P Kirchner, and
K Parent
October 2003,
AJR. American journal of roentgenology,
R G Norfleet, and
M E Ryan, and
J B Wyman, and
R A Rhodes, and
J F Nunez, and
J P Kirchner, and
K Parent
February 1982,
Gastrointestinal endoscopy,
R G Norfleet, and
M E Ryan, and
J B Wyman, and
R A Rhodes, and
J F Nunez, and
J P Kirchner, and
K Parent
October 1974,
Proceedings of the Royal Society of Medicine,
R G Norfleet, and
M E Ryan, and
J B Wyman, and
R A Rhodes, and
J F Nunez, and
J P Kirchner, and
K Parent
September 1988,
Gut,
R G Norfleet, and
M E Ryan, and
J B Wyman, and
R A Rhodes, and
J F Nunez, and
J P Kirchner, and
K Parent
January 2007,
Journal of gastrointestinal cancer,
R G Norfleet, and
M E Ryan, and
J B Wyman, and
R A Rhodes, and
J F Nunez, and
J P Kirchner, and
K Parent
September 1984,
The Journal of family practice,
R G Norfleet, and
M E Ryan, and
J B Wyman, and
R A Rhodes, and
J F Nunez, and
J P Kirchner, and
K Parent
January 2002,
Gastrointestinal endoscopy clinics of North America,
R G Norfleet, and
M E Ryan, and
J B Wyman, and
R A Rhodes, and
J F Nunez, and
J P Kirchner, and
K Parent
November 2000,
Gastroenterology,
