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Using a series of cold-sensitive variants of chemically transformed BHK-21 cells, revertants to the normal phenotype derived from a dimethyl-nitrosamine transformed clone of BHK-21 as well as revertants to the normal phenotype derived from polyoma transformed BHK-21 cells we have demonstrated that the surface phenotype described by enhanced agglutinability with Con A and WGA can be dissociated from the transformed phenotype described by anchorage independence (growth in semisolid medium). Specifically we have demonstrated that the surface characteristic of enhanced agglutinability may be found in a variety of cell lines which fail to display to grow in agar. Our work clearly shows that the two phenotypes described are not concomitantly controlled and tends to suggest that the phenotype of enhanced lectin agglutinability may be dissociated from the transformed phenotype.
K D Noonan, and
N Bouck, and
G di Mayorica
July 1973,
Biochimica et biophysica acta,
K D Noonan, and
N Bouck, and
G di Mayorica
January 1983,
Cytogenetics and cell genetics,
K D Noonan, and
N Bouck, and
G di Mayorica
July 1980,
International journal of cancer,
K D Noonan, and
N Bouck, and
G di Mayorica
October 1990,
Cancer research,
K D Noonan, and
N Bouck, and
G di Mayorica
January 1976,
The Journal of cell biology,
K D Noonan, and
N Bouck, and
G di Mayorica
April 1982,
Medical hypotheses,
K D Noonan, and
N Bouck, and
G di Mayorica
January 1992,
Folia parasitologica,
K D Noonan, and
N Bouck, and
G di Mayorica
September 1985,
Blood,
K D Noonan, and
N Bouck, and
G di Mayorica
November 1981,
Biochimica et biophysica acta,
K D Noonan, and
N Bouck, and
G di Mayorica
July 1982,
Tsitologiia,
