BIOMAT Database Logo BIOMAT Database Logo

Complications associated with central venous catheters inserted in critically ill neonates. 1991

V Hruszkewycz, and P C Holtrop, and D G Batton, and R S Morden, and P Gibson, and J D Band
Department of Epidemiology, William Beaumont Hospital, Royal Oak, Michigan 48073.

OBJECTIVE To assess the incidence and spectrum of complications associated with central venous catheter (CVC) placement in the critically ill infant. METHODS A prospective study of all babies hospitalized in a neonatal intensive care unit (NICU) from January 1989 to December 1989. Potential risk factors associated with infection were evaluated by a case-control comparison. METHODS Conducted at a university-affiliated, tertiary care community hospital. METHODS Neonates requiring intensive care and a central venous catheter. Controls consisted of noninfected babies. RESULTS Of 263 critically ill neonates, only 13 (4.9%) required a CVC insertion. Seventeen CVCs were placed in these 13 neonates for a total duration of 600 days (median, 32 days/cannula). Fifteen (88%) of these cannulas had one or more complications during its catheter life including dislodgement or leakage (53%), occlusion or thrombosis (47%), infections (29%), or minor bleeding (12%). Five babies (29%) developed 6 episodes of bloodstream infection including 3 sporadic cases due to Staphylococcus epidermidis and a cluster of fungemia due to Malassezia furfur associated with lipid emulsion therapy. Infants with a CVC-associated infection were a younger gestational age (24 weeks versus 32 weeks, p = .04) and weighed less at birth (580 g versus 1285 g, p = .02). The overall rate of bloodstream infection was one episode per 100 days of catheter use. CONCLUSIONS CVCs may be lifesaving to a critically ill neonate, but complications occur frequently. Use must be restricted to infants in whom alternate delivery routes of intravenous therapy or support are otherwise unavailable.

UI MeSH Term Description Entries
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D007363 Intensive Care Units, Neonatal Hospital units providing continuing surveillance and care to acutely ill newborn infants. Neonatal Intensive Care Unit,Neonatal Intensive Care Units,Newborn Intensive Care Unit,Newborn Intensive Care Units,ICU, Neonatal,Neonatal ICU,Newborn ICU,Newborn Intensive Care Units (NICU),ICU, Newborn,ICUs, Neonatal,ICUs, Newborn,Neonatal ICUs,Newborn ICUs
D008297 Male Males
D008824 Michigan State bounded on the north by the Great Lakes, on the east by Canada, on the south by Wisconsin, Indiana, and Ohio, and on the west by Lake Michigan and Wisconsin.
D011446 Prospective Studies Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group. Prospective Study,Studies, Prospective,Study, Prospective
D001724 Birth Weight The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms. Birthweight,Birth Weights,Birthweights,Weight, Birth,Weights, Birth
D002405 Catheterization, Central Venous Placement of an intravenous CATHETER in the subclavian, jugular, or other central vein. Central Venous Catheterization,Venous Catheterization, Central,Catheterization, Central,Central Catheterization,Catheterizations, Central,Catheterizations, Central Venous,Central Catheterizations,Central Venous Catheterizations,Venous Catheterizations, Central
D003428 Cross Infection Any infection which a patient contracts in a health-care institution. Hospital Infections,Nosocomial Infections,Health Care Associated Infection,Health Care Associated Infections,Healthcare Associated Infections,Infection, Cross,Infections, Hospital,Infections, Nosocomial,Cross Infections,Healthcare Associated Infection,Hospital Infection,Infection, Healthcare Associated,Infection, Hospital,Infection, Nosocomial,Infections, Cross,Infections, Healthcare Associated,Nosocomial Infection
D005260 Female Females
D005865 Gestational Age The age of the conceptus, beginning from the time of FERTILIZATION. In clinical obstetrics, the gestational age is often estimated from the onset of the last MENSTRUATION which is about 2 weeks before OVULATION and fertilization. It is also estimated to begin from fertilization, estrus, coitus, or artificial insemination. Embryologic Age,Fetal Maturity, Chronologic,Chronologic Fetal Maturity,Fetal Age,Maturity, Chronologic Fetal,Age, Embryologic,Age, Fetal,Age, Gestational,Ages, Embryologic,Ages, Fetal,Ages, Gestational,Embryologic Ages,Fetal Ages,Gestational Ages

Related Publications

V Hruszkewycz, and P C Holtrop, and D G Batton, and R S Morden, and P Gibson, and J D Band
Peripherally inserted central venous catheters in critically ill premature neonates.
January 2013, The journal of vascular access,
V Hruszkewycz, and P C Holtrop, and D G Batton, and R S Morden, and P Gibson, and J D Band
Complications of percutaneously inserted central venous catheters in Japanese neonates.
October 2008, Pediatrics international : official journal of the Japan Pediatric Society,
V Hruszkewycz, and P C Holtrop, and D G Batton, and R S Morden, and P Gibson, and J D Band
Effect of heparin and other factors associated with complications of peripherally inserted central venous catheters in neonates.
November 2012, Journal of perinatology : official journal of the California Perinatal Association,
V Hruszkewycz, and P C Holtrop, and D G Batton, and R S Morden, and P Gibson, and J D Band
Peripherally inserted central catheters in critically ill patients - complications and its prevention: A review.
January 2019, International journal of nursing sciences,
V Hruszkewycz, and P C Holtrop, and D G Batton, and R S Morden, and P Gibson, and J D Band
Lower risk of bloodstream infections for peripherally inserted central catheters compared to central venous catheters in critically ill patients.
November 2022, Antimicrobial resistance and infection control,
V Hruszkewycz, and P C Holtrop, and D G Batton, and R S Morden, and P Gibson, and J D Band
Focus on peripherally inserted central catheters in critically ill patients.
November 2014, World journal of critical care medicine,
V Hruszkewycz, and P C Holtrop, and D G Batton, and R S Morden, and P Gibson, and J D Band
Infectious complications of percutaneously inserted central venous catheters.
August 1985, Acta anaesthesiologica Scandinavica,
V Hruszkewycz, and P C Holtrop, and D G Batton, and R S Morden, and P Gibson, and J D Band
Central venous catheters in neonates: old territory, new frontiers. Invited commentary to peripherally inserted central venous catheters in critically ill premature neonates, by Ozkiraz et al, J Vasc Access 2013;14(4):320-324.
January 2013, The journal of vascular access,
V Hruszkewycz, and P C Holtrop, and D G Batton, and R S Morden, and P Gibson, and J D Band
The safety of peripherally inserted central venous catheters in critically ill patients: A retrospective observational study.
April 2023, The journal of vascular access,
V Hruszkewycz, and P C Holtrop, and D G Batton, and R S Morden, and P Gibson, and J D Band
Usefulness of radiographic imaging of percutaneously inserted central venous catheters in critically ill infants and children.
January 2016, Intensive care medicine,
Copied contents to your clipboard!