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The activity of soluble protein kinase (ATP:protein phosphotransferase,EC 2.7.1.37) and pattern of nuclear protein phosphorylation was monitored in cultured rat pineal glands during the induction of serotonin N-acetyltransferase (acetyl-CoA:serotonin N-acetyltransferase;EC 2.3.1.5)by l-isoproterenol. A nuclear protein appears to be phosphorylated during the early stages of enzyme induction but is not phosphorylated at later stages of induction. This correlates well with the need for RNA synthesis associated with the induction process. The nuclear protein was also phosphorylated when the pineal glands were treated with dibutyryl 3':5'-cyclic AMP. The soluble protein kinase activity appeared to decline during mid-to-late stages of enzyme induction, but there was no concomitant increase in the particulate protein kinase activity.
K E Winters, and
J J Morrissey, and
P J Loos, and
W Lovenberg
November 1978,
Archives of biochemistry and biophysics,
K E Winters, and
J J Morrissey, and
P J Loos, and
W Lovenberg
January 1981,
Essays in neurochemistry and neuropharmacology,
K E Winters, and
J J Morrissey, and
P J Loos, and
W Lovenberg
May 1992,
Biochemical Society transactions,
K E Winters, and
J J Morrissey, and
P J Loos, and
W Lovenberg
January 1975,
Experientia,
K E Winters, and
J J Morrissey, and
P J Loos, and
W Lovenberg
February 1978,
Biochemical pharmacology,
K E Winters, and
J J Morrissey, and
P J Loos, and
W Lovenberg
January 1982,
Progress in clinical and biological research,
K E Winters, and
J J Morrissey, and
P J Loos, and
W Lovenberg
December 1995,
Science (New York, N.Y.),
K E Winters, and
J J Morrissey, and
P J Loos, and
W Lovenberg
January 1978,
Brain research,
K E Winters, and
J J Morrissey, and
P J Loos, and
W Lovenberg
August 1985,
Journal of neurochemistry,
K E Winters, and
J J Morrissey, and
P J Loos, and
W Lovenberg
December 1981,
Journal of neurochemistry,
