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A case is reported of primary malignant non-Hodgkin's lymphoma of the colon of a 85-year-old woman. The clinical manifestations and the X-ray pattern were those of cancer. The diagnosis was established on post-mortem examination. Histologically this was a centroblastic-centrocytic lymphoma of Brill-Symmers with low-grade malignancy. The clinical, diagnostic, prognostic and therapeutic problems in malignant non-Hodgkin's lymphomas of the colon are discussed.
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