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In experiments on 406 CBA mice the effect of antimicrobial preparations, used in combination with total gnotobiotic isolation, on the survival rate of totally irradiated animals was studied. The use of antimicrobial preparations was shown to considerably enhance the survival rate of these animals. Cyprofloxacin, a new preparation of the kinolone row, exhibited a good effect ensuring selective decontamination of the intestine. The use of cyprofloxacin prior to irradiation with the subsequent isolation of the animals in gnotobiotic chambers increased the survival rate of these animals by 2.7 times. But the maximum survival rate of irradiated mice was observed in those cases when antimicrobial preparations were used both before and after irradiation in combination with the total gnotobiotic isolation of the animals.
L A Romanchuk, and
V M Korshunov, and
W Busch, and
A A Ivanov, and
N P Tarabrina
January 2000,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
L A Romanchuk, and
V M Korshunov, and
W Busch, and
A A Ivanov, and
N P Tarabrina
May 1967,
Meditsinskaia radiologiia,
L A Romanchuk, and
V M Korshunov, and
W Busch, and
A A Ivanov, and
N P Tarabrina
January 1968,
Voprosy onkologii,
L A Romanchuk, and
V M Korshunov, and
W Busch, and
A A Ivanov, and
N P Tarabrina
January 1971,
Radiobiologia, radiotherapia,
L A Romanchuk, and
V M Korshunov, and
W Busch, and
A A Ivanov, and
N P Tarabrina
January 1992,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
L A Romanchuk, and
V M Korshunov, and
W Busch, and
A A Ivanov, and
N P Tarabrina
November 1979,
Khirurgiia,
L A Romanchuk, and
V M Korshunov, and
W Busch, and
A A Ivanov, and
N P Tarabrina
January 1984,
Vestnik Akademii meditsinskikh nauk SSSR,
L A Romanchuk, and
V M Korshunov, and
W Busch, and
A A Ivanov, and
N P Tarabrina
January 1961,
Farmakologiia i toksikologiia,
L A Romanchuk, and
V M Korshunov, and
W Busch, and
A A Ivanov, and
N P Tarabrina
February 1960,
Meditsinskaia radiologiia,
L A Romanchuk, and
V M Korshunov, and
W Busch, and
A A Ivanov, and
N P Tarabrina
August 1968,
Antibiotiki,
