Biomaterial Database

Antigenic shift of visna virus in persistently infected sheep. 1977

O Narayan, and D E Griffin, and J Chase

Visna viruses isolated from persistently infected sheep were antigenically distinct from the plaque-purified virus used for inoculation. The selection of antigenic variants under antibody pressure, thought to occur in vivo, was reproduced in sheep cell cultures inoculated with plaque-purified visna virus and maintained in antibody. Antigenic shift may be a mechanism for persistence of virus in slow or recurrent viral infections.

UI	MeSH Term	Description	Entries
D007962	Leukocytes	White blood cells. These include granular leukocytes (BASOPHILS; EOSINOPHILS; and NEUTROPHILS) as well as non-granular leukocytes (LYMPHOCYTES and MONOCYTES).	Blood Cells, White,Blood Corpuscles, White,White Blood Cells,White Blood Corpuscles,Blood Cell, White,Blood Corpuscle, White,Corpuscle, White Blood,Corpuscles, White Blood,Leukocyte,White Blood Cell,White Blood Corpuscle
D011648	Pulmonary Adenomatosis, Ovine	A contagious, neoplastic, pulmonary disease of sheep characterized by hyperplasia and hypertrophy of pneumocytes and epithelial cells of the lung. It is caused by JAAGSIEKTE SHEEP RETROVIRUS.	Adenomatosis, Pulmonary, Ovine,Carcinoma, Ovine Pulmonary,Jaagsiekte,Adenomatosis, Ovine Pulmonary,Ovine Pulmonary Adenomatosis,Ovine Pulmonary Carcinoma,Pulmonary Ovine Adenomatosis,Adenomatoses, Ovine Pulmonary,Adenomatoses, Pulmonary Ovine,Adenomatosis, Pulmonary Ovine,Carcinomas, Ovine Pulmonary,Ovine Adenomatoses, Pulmonary,Ovine Adenomatosis, Pulmonary,Ovine Pulmonary Adenomatoses,Ovine Pulmonary Carcinomas,Pulmonary Adenomatoses, Ovine,Pulmonary Carcinoma, Ovine,Pulmonary Carcinomas, Ovine,Pulmonary Ovine Adenomatoses
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D000956	Antigens, Viral	Substances elaborated by viruses that have antigenic activity.	Viral Antigen,Viral Antigens,Antigen, Viral
D012328	RNA Viruses	Viruses whose genetic material is RNA.	RNA Rodent Viruses,RNA Rodent Virus,RNA Virus,Rodent Virus, RNA,Rodent Viruses, RNA,Virus, RNA,Virus, RNA Rodent,Viruses, RNA,Viruses, RNA Rodent
D012756	Sheep	Any of the ruminant mammals with curved horns in the genus Ovis, family Bovidae. They possess lachrymal grooves and interdigital glands, which are absent in GOATS.	Ovis,Sheep, Dall,Dall Sheep,Ovis dalli
D014790	Visna-maedi virus	A species of LENTIVIRUS, subgenus ovine-caprine lentiviruses (LENTIVIRUSES, OVINE-CAPRINE), that can cause chronic pneumonia (maedi), mastitis, arthritis, and encephalomyelitis (visna) in sheep. Maedi is a progressive pneumonia of sheep which is similar to but not the same as jaagsiekte (PULMONARY ADENOMATOSIS, OVINE). Visna is a demyelinating leukoencephalomyelitis of sheep which is similar to but not the same as SCRAPIE.	Maedi Virus,Maedi-Visna Virus,Visna Virus,Maedi Viruses,Maedi Visna Virus,Visna Maedi Virus