BIOMAT Database Logo BIOMAT Database Logo

Biofunctionalized tilted Fiber Bragg Gratings for label-free immunosensing. 2008

Séverine Maguis, and Guillaume Laffont, and Pierre Ferdinand, and Benjamin Carbonnier, and Khémara Kham, and Tahar Mekhalif, and Marie-Claude Millot
CEA, LIST, Laboratoire de Mesures Optiques, Centre d'Etudes de Saclay, Gif-sur-Yvette cedex, France. severine.maguis@cea.fr

We present a study aimed at developing a label-free optical fiber biosensor for detection and quantification of biomolecules in real-time. The biosensor based on a Tilted Fiber Bragg Grating (TFBG) transduces a binding event between the probe and target molecules into a change in the refractive index of the medium surrounding the fiber. This work describes the experimental results obtained with three methods for immobilizing biomolecular probes on a TFBG silica cladding surface. Bovine serum albumin (BSA) and anti-BSA are used to assess the performances of the TFBG based biosensor in each configuration.

UI MeSH Term Description Entries
D007118 Immunoassay A technique using antibodies for identifying or quantifying a substance. Usually the substance being studied serves as antigen both in antibody production and in measurement of antibody by the test substance. Immunochromatographic Assay,Assay, Immunochromatographic,Assays, Immunochromatographic,Immunoassays,Immunochromatographic Assays
D012031 Refractometry Measurement of the index of refraction (the ratio of the velocity of light or other radiation in the first of two media to its velocity in the second as it passes from one into the other). Refractive Index,Index, Refractive,Indices, Refractive,Refractive Indices
D004867 Equipment Design Methods and patterns of fabricating machines and related hardware. Design, Equipment,Device Design,Medical Device Design,Design, Medical Device,Designs, Medical Device,Device Design, Medical,Device Designs, Medical,Medical Device Designs,Design, Device,Designs, Device,Designs, Equipment,Device Designs,Equipment Designs
D012680 Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) Specificity,Sensitivity,Specificity and Sensitivity
D012710 Serum Albumin, Bovine Serum albumin from cows, commonly used in in vitro biological studies. (From Stedman, 25th ed) Fetal Bovine Serum,Fetal Calf Serum,Albumin Bovine,Bovine Albumin,Bovine Serum Albumin,Albumin, Bovine,Albumin, Bovine Serum,Bovine Serum, Fetal,Bovine, Albumin,Calf Serum, Fetal,Serum, Fetal Bovine,Serum, Fetal Calf
D013194 Staining and Labeling The marking of biological material with a dye or other reagent for the purpose of identifying and quantitating components of tissues, cells or their extracts. Histological Labeling,Staining,Histological Labelings,Labeling and Staining,Labeling, Histological,Labelings, Histological,Stainings
D015203 Reproducibility of Results The statistical reproducibility of measurements (often in a clinical context), including the testing of instrumentation or techniques to obtain reproducible results. The concept includes reproducibility of physiological measurements, which may be used to develop rules to assess probability or prognosis, or response to a stimulus; reproducibility of occurrence of a condition; and reproducibility of experimental results. Reliability and Validity,Reliability of Result,Reproducibility Of Result,Reproducibility of Finding,Validity of Result,Validity of Results,Face Validity,Reliability (Epidemiology),Reliability of Results,Reproducibility of Findings,Test-Retest Reliability,Validity (Epidemiology),Finding Reproducibilities,Finding Reproducibility,Of Result, Reproducibility,Of Results, Reproducibility,Reliabilities, Test-Retest,Reliability, Test-Retest,Result Reliabilities,Result Reliability,Result Validities,Result Validity,Result, Reproducibility Of,Results, Reproducibility Of,Test Retest Reliability,Validity and Reliability,Validity, Face
D015374 Biosensing Techniques Any of a variety of procedures which use biomolecular probes to measure the presence or concentration of biological molecules, biological structures, microorganisms, etc., by translating a biochemical interaction at the probe surface into a quantifiable physical signal. Bioprobes,Biosensors,Electrodes, Enzyme,Biosensing Technics,Bioprobe,Biosensing Technic,Biosensing Technique,Biosensor,Electrode, Enzyme,Enzyme Electrode,Enzyme Electrodes,Technic, Biosensing,Technics, Biosensing,Technique, Biosensing,Techniques, Biosensing
D017076 Computer-Aided Design The use of computers for designing and/or manufacturing of anything, including drugs, surgical procedures, orthotics, and prosthetics. CAD-CAM,Computer-Aided Manufacturing,Computer-Assisted Design,Computer-Assisted Manufacturing,Computer Aided Design,Computer Aided Manufacturing,Computer Assisted Design,Computer Assisted Manufacturing,Computer-Aided Designs,Computer-Assisted Designs,Design, Computer-Aided,Design, Computer-Assisted,Designs, Computer-Aided,Designs, Computer-Assisted,Manufacturing, Computer-Aided,Manufacturing, Computer-Assisted
D019544 Equipment Failure Analysis The evaluation of incidents involving the loss of function of a device. These evaluations are used for a variety of purposes such as to determine the failure rates, the causes of failures, costs of failures, and the reliability and maintainability of devices. Materials Failure Analysis,Prosthesis Failure Analysis,Analysis, Equipment Failure,Analysis, Materials Failure,Analysis, Prosthesis Failure,Analyses, Equipment Failure,Analyses, Materials Failure,Analyses, Prosthesis Failure,Equipment Failure Analyses,Failure Analyses, Equipment,Failure Analyses, Materials,Failure Analyses, Prosthesis,Failure Analysis, Equipment,Failure Analysis, Materials,Failure Analysis, Prosthesis,Materials Failure Analyses,Prosthesis Failure Analyses

Related Publications

Séverine Maguis, and Guillaume Laffont, and Pierre Ferdinand, and Benjamin Carbonnier, and Khémara Kham, and Tahar Mekhalif, and Marie-Claude Millot
Functionalized etched tilted fiber Bragg grating aptasensor for label-free protein detection.
December 2019, Biosensors & bioelectronics,
Séverine Maguis, and Guillaume Laffont, and Pierre Ferdinand, and Benjamin Carbonnier, and Khémara Kham, and Tahar Mekhalif, and Marie-Claude Millot
Gold-coated tilted fiber Bragg gratings for lead ion sensing.
September 2023, Optics express,
Séverine Maguis, and Guillaume Laffont, and Pierre Ferdinand, and Benjamin Carbonnier, and Khémara Kham, and Tahar Mekhalif, and Marie-Claude Millot
Tilted Bragg gratings in step-index polymer optical fiber.
December 2014, Optics letters,
Séverine Maguis, and Guillaume Laffont, and Pierre Ferdinand, and Benjamin Carbonnier, and Khémara Kham, and Tahar Mekhalif, and Marie-Claude Millot
Plasmon resonances in gold-coated tilted fiber Bragg gratings.
February 2007, Optics letters,
Séverine Maguis, and Guillaume Laffont, and Pierre Ferdinand, and Benjamin Carbonnier, and Khémara Kham, and Tahar Mekhalif, and Marie-Claude Millot
Label-Free DNA Detection Using Etched Tilted Bragg Fiber Grating-Based Biosensor.
August 2023, Sensors (Basel, Switzerland),
Séverine Maguis, and Guillaume Laffont, and Pierre Ferdinand, and Benjamin Carbonnier, and Khémara Kham, and Tahar Mekhalif, and Marie-Claude Millot
Tilted fiber Bragg gratings in multicore optical fibers for optical sensing.
April 2017, Optics letters,
Séverine Maguis, and Guillaume Laffont, and Pierre Ferdinand, and Benjamin Carbonnier, and Khémara Kham, and Tahar Mekhalif, and Marie-Claude Millot
Twisted tilted fiber Bragg gratings: new structures and polarization properties.
September 2018, Optics letters,
Séverine Maguis, and Guillaume Laffont, and Pierre Ferdinand, and Benjamin Carbonnier, and Khémara Kham, and Tahar Mekhalif, and Marie-Claude Millot
BIO bragg gratings on microfibers for label-free biosensing.
March 2021, Biosensors & bioelectronics,
Séverine Maguis, and Guillaume Laffont, and Pierre Ferdinand, and Benjamin Carbonnier, and Khémara Kham, and Tahar Mekhalif, and Marie-Claude Millot
Coupling characteristics of cladding modes in tilted optical fiber bragg gratings.
August 1998, Applied optics,
Séverine Maguis, and Guillaume Laffont, and Pierre Ferdinand, and Benjamin Carbonnier, and Khémara Kham, and Tahar Mekhalif, and Marie-Claude Millot
Polarization independent Bragg gratings using tilted subwavelength grating waveguide Bragg gratings.
January 2023, Optics express,
Copied contents to your clipboard!