Biomaterial Database

Circulating antibodies against thermophilic actinomycetes in farmers and mushroom workers. 1991

Y E Shen, and V P Kurup, and J N Fink

Research Service, Zablocki Veterans Affairs Medical Center, Milwaukee, WI.

Sera from individuals exposed to moldy hay, mushroom compost and unexposed individuals, were studied for antibodies against thermophilic actinomycetes and Aspergillus fumigatus. Antigens extracted from Thermoactinomyces vulgaris strains isolated from China were used in the study along with antigens from standard strains to screen the sera of individuals exposed to farms and unexposed controls from both China and the United States. It was found that very little antibody response to A. fumigatus and F. rectivirgula was demonstrated in the sera of both individuals exposed to farm environments and unexposed controls. On the other hand, antibodies to Thermoactinomyces vulgaris and T. candidus strains were seen in the sera of both exposed and unexposed individuals from China, indicating that these organisms are prevalent in all the environments of China. The results also indicate that antigenicity of the strains vary considerably in their reactivity with sera.

UI	MeSH Term	Description	Entries
D007074	Immunoglobulin G	The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.	Gamma Globulin, 7S,IgG,IgG Antibody,Allerglobuline,IgG(T),IgG1,IgG2,IgG2A,IgG2B,IgG3,IgG4,Immunoglobulin GT,Polyglobin,7S Gamma Globulin,Antibody, IgG,GT, Immunoglobulin
D008848	Micromonosporaceae	A family of gram-positive, saprophytic bacteria occurring in soil and aquatic environments.
D002681	China	A country spanning from central Asia to the Pacific Ocean.	Inner Mongolia,Manchuria,People's Republic of China,Sinkiang,Mainland China
D005203	Farmer's Lung	A form of alveolitis or pneumonitis due to an acquired hypersensitivity to inhaled antigens associated with farm environment. Antigens in the farm dust are commonly from bacteria actinomycetes (SACCHAROPOLYSPORA and THERMOACTINOMYCES), fungi, and animal proteins in the soil, straw, crops, pelts, serum, and excreta.	Mushroom Worker's Lung,Farmer Lung,Farmer's Lungs,Farmers Lung,Mushroom Worker Lung,Mushroom Worker's Lungs,Mushroom Workers Lung
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000382	Agricultural Workers' Diseases	Diseases in persons engaged in cultivating and tilling soil, growing plants, harvesting crops, raising livestock, or otherwise engaged in husbandry and farming. The diseases are not restricted to farmers in the sense of those who perform conventional farm chores: the heading applies also to those engaged in the individual activities named above, as in those only gathering harvest or in those only dusting crops.	Agricultural Worker Disease,Agricultural Worker's Disease,Agricultural Worker Diseases,Agricultural Worker's Diseases,Agricultural Workers Disease,Agricultural Workers Diseases,Agricultural Workers' Disease,Disease, Agricultural Worker,Disease, Agricultural Worker's,Disease, Agricultural Workers',Diseases, Agricultural Worker,Diseases, Agricultural Worker's,Diseases, Agricultural Workers',Worker Disease, Agricultural,Worker Diseases, Agricultural,Worker's Disease, Agricultural,Worker's Diseases, Agricultural,Workers' Disease, Agricultural,Workers' Diseases, Agricultural
D000907	Antibodies, Bacterial	Immunoglobulins produced in a response to BACTERIAL ANTIGENS.	Bacterial Antibodies
D000908	Antibodies, Fungal	Immunoglobulins produced in a response to FUNGAL ANTIGENS.	Fungal Antibodies
D001232	Aspergillus fumigatus	A species of imperfect fungi from which the antibiotic fumigatin is obtained. Its spores may cause respiratory infection in birds and mammals.	Aspergillus fumigates,Neosartorya fumigata,Sartorya fumigata
D001487	Basidiomycota	A phylum of fungi that produce their sexual spores (basidiospores) on the outside of the basidium. It includes forms commonly known as mushrooms, boletes, puffballs, earthstars, stinkhorns, bird's-nest fungi, jelly fungi, bracket or shelf fungi, and rust and smut fungi.	Basidiomycetes,Basidiomycete,Basidiomycotas