OBJECTIVE To investigate the chemical constituents of the roots of Angelica polymorpha. METHODS Silica gel column chromatography was employed for the isolation and purification of chemical constituents. The structures were identified on the basis of spectral data and chemical evidence. RESULTS Fourteen compounds were isolated and identified as follows, 5-hydroxy-2-[(angeloyloxy) methyl] furan [3', 2': 6, 7] chromone (1), octacosanoic acid (2), isoimperatorin (3), 3'S-(-)-O-acetylhamaudol (4), bergapten (5), iso-oxypeucedanin (6), beta-sitosterol (7), angeliticin A (8) , saxalin (9), pabulenol (10), noreugenin (11), oxypeucedanin hydrate (12), daucosterol (13), sucrose (14). CONCLUSIONS Compound 1 is a new chromone, named polymorchromone A. Compounds 2, 4, 11, 13, 14 were isolated from A. polymorpha for the first time.