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Renal cell carcinoma (RCC) is a relatively uncommon cancer in renal transplant patients. From 1968 to 1987, 101 cases of RCC of native kidneys have been reported to the Cincinnati Transplant Tumor Registry. We describe here a case of metastatic RCC associated with acquired cystic kidney disease (ACKD) 15 years after successful renal transplantation. The patient presented with a subcutaneous nodule, which led to discovery of a large primary tumor in the left kidney. ACKD was present in the atrophic right kidney. The reported cases of ACKD-associated RCC in renal transplant recipients were reviewed. Most of these cases are middle-aged men with a long posttransplant course, good graft function, and usage of azathioprine and prednisone as immunosuppressive agents. ACKD can develop or persist and progress to RCC many years after successful renal transplantation. Transplant patients with flank pain, hematuria, or other suspicious symptoms should have imaging studies of their native kidneys.
Y H Lien, and
I Kam, and
P F Shanley, and
G P Schröter
May 1990,
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Y H Lien, and
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G P Schröter
May 1987,
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Y H Lien, and
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G P Schröter
January 1995,
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Y H Lien, and
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P F Shanley, and
G P Schröter
January 1990,
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Y H Lien, and
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G P Schröter
January 1983,
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Y H Lien, and
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G P Schröter
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Y H Lien, and
I Kam, and
P F Shanley, and
G P Schröter
March 2022,
Clinical imaging,
Y H Lien, and
I Kam, and
P F Shanley, and
G P Schröter
April 2023,
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Y H Lien, and
I Kam, and
P F Shanley, and
G P Schröter
July 2018,
Nephrology (Carlton, Vic.),
Y H Lien, and
I Kam, and
P F Shanley, and
G P Schröter
February 2010,
Histopathology,
