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[Studies on chemical constituents of Daphne genkwa]. 2009

Cai-Fang Wang, and Rao-Rao Li, and Lan-Lan Huang, and Li-Qun Zhong, and Si-Tong Yuan
Institute of Chinese Materia Medica, China Academy of Chinese Medical Science, Beijing 100700, China. cfwang@zzu.edu.cn

OBJECTIVE To study the chemical constituents of the flower buds of Daphne genkwa. METHODS The constituents of petroleum ether and ethyl acetate-soluble portions were isolated and purified by means of chromatography, then they were identified by their physico-chemical characteristics and spectral features. RESULTS Ten compounds were isolated and identified as octacosane (1), dotriacontane (2), beta-sitosterol (3), 4', 7-dimethoxy-5-hydroxyflovone (4), aurantiamide acetate (5), genkwanin (6), luteolin (7), apigenin (8), 3'-hydroxygenkwanin (9) and daphnoretin (10). CONCLUSIONS Compound 1 and 2 are isolated from this plant for the first time.

UI MeSH Term Description Entries
D010946 Plants, Medicinal Plants whose roots, leaves, seeds, bark, or other constituent parts possess therapeutic, tonic, purgative, curative or other pharmacologic attributes, when administered to man or animals. Herbs, Medicinal,Medicinal Herbs,Healing Plants,Medicinal Plants,Pharmaceutical Plants,Healing Plant,Herb, Medicinal,Medicinal Herb,Medicinal Plant,Pharmaceutical Plant,Plant, Healing,Plant, Medicinal,Plant, Pharmaceutical,Plants, Healing,Plants, Pharmaceutical
D003374 Coumarins Synthetic or naturally occurring substances related to coumarin, the delta-lactone of coumarinic acid. 1,2-Benzopyrone Derivatives,1,2-Benzopyrones,Coumarin Derivative,Coumarine,1,2-Benzo-Pyrones,Benzopyran-2-ones,Coumarin Derivatives,Coumarines,1,2 Benzo Pyrones,1,2 Benzopyrone Derivatives,1,2 Benzopyrones,Benzopyran 2 ones,Derivative, Coumarin,Derivatives, 1,2-Benzopyrone,Derivatives, Coumarin
D003931 Diacetyl Carrier of aroma of butter, vinegar, coffee, and other foods. 2,3-Butanedione,Biacetyl,Diketobutane,Dimethyldiketone,Dimethylglyoxal,2,3 Butanedione
D004151 Dipeptides Peptides composed of two amino acid units. Dipeptide
D000473 Alkanes The generic name for the group of aliphatic hydrocarbons Cn-H2n+2. They are denoted by the suffix -ane. (Grant & Hackh's Chemical Dictionary, 5th ed) Alkane
D012855 Sitosterols A family of sterols commonly found in plants and plant oils. Alpha-, beta-, and gamma-isomers have been characterized.
D015394 Molecular Structure The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds. Structure, Molecular,Molecular Structures,Structures, Molecular
D047309 Flavones A group of 4-keto-FLAVONOIDS. 2-Phenyl-2-Ene-Benzopyran-4-One Compounds
D047310 Apigenin 5,7,4'-trihydroxy-flavone, one of the FLAVONES.
D047311 Luteolin 5,7,3',4'-tetrahydroxy-flavone, one of the FLAVONES. 3',4',5,7-Tetrahydroxy-Flavone,3',4',5,7-Tetrahydroxyflavone,Luteoline

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