Biomaterial Database

Clinical study of the anticaries efficacy of three fluoride dentifrices containing anticalculus ingredients: three-year (final) results. 1990

L W Ripa, and G S Leske, and C W Triol, and A R Volpe

School of Dental Medicine, State University of New York, Stony Brook.

A 3-year double blind clinical trial was conducted to compare the caries inhibition of an A.D.A.-accepted fluoride dentifrice to the caries inhibitions provided by three fluoride dentifrices containing anticalculus agents. All dentifrices used a compatible silicon dioxide abrasive system. The initial mean age of the subjects was 9.9 yrs and they resided in F-deficient (F less than 0.3 ppm) communities on Long Island, NY. Caries activity in all groups was low with the average annual increment being less than one surface. There were no statistically significant differences in any of the dental parameters tested, DMFS, DMFT, and buccolingual, mesiodistal and occlusal surface increments. It was concluded that the presence of anticalculus agents, specifically soluble pyrophosphates, zinc chloride and zinc oxide, do not interfere with the caries inhibition benefits of fluoride in a compatible dentifrice formulation.

UI	MeSH Term	Description	Entries
D009518	New York	State bounded on the north by Lake Ontario and Canada, on the east by Vermont, Massachusetts, and Connecticut, on the south by the Atlantic Ocean, New Jersey, and Pennsylvania, and on the west by Pennsylvania, Lake Erie, and Canada.
D011756	Diphosphates	Inorganic salts of phosphoric acid that contain two phosphate groups.	Diphosphate,Pyrophosphate Analog,Pyrophosphates,Pyrophosphate Analogs,Analog, Pyrophosphate
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D002712	Chlorides	Inorganic compounds derived from hydrochloric acid that contain the Cl- ion.	Chloride,Chloride Ion Level,Ion Level, Chloride,Level, Chloride Ion
D002951	Citrates	Derivatives of CITRIC ACID.
D003728	Dental Calculus	Abnormal concretion or calcified deposit that forms around the teeth or dental prostheses.	Tartar,Calculus, Dental
D003731	Dental Caries	Localized destruction of the tooth surface initiated by decalcification of the enamel followed by enzymatic lysis of organic structures and leading to cavity formation. If left unchecked, the cavity may penetrate the enamel and dentin and reach the pulp.	Caries, Dental,Carious Lesions,Dental Cavities,Dental Cavity,Dental Decay,Dental White Spots,Carious Dentin,Decay, Dental,Dental White Spot,White Spot, Dental,White Spots, Dental,Carious Dentins,Carious Lesion,Cavities, Dental,Cavity, Dental,Dentin, Carious,Dentins, Carious,Lesion, Carious,Lesions, Carious,Spot, Dental White,Spots, Dental White
D003802	Dentifrices	Any preparations used for cleansing teeth; they usually contain an abrasive, detergent, binder and flavoring agent and may exist in the form of liquid, paste or powder; may also contain medicaments and caries preventives.	Polishes, Dental,Dental Polishes,Dentifrice
D004311	Double-Blind Method	A method of studying a drug or procedure in which both the subjects and investigators are kept unaware of who is actually getting which specific treatment.	Double-Masked Study,Double-Blind Study,Double-Masked Method,Double Blind Method,Double Blind Study,Double Masked Method,Double Masked Study,Double-Blind Methods,Double-Blind Studies,Double-Masked Methods,Double-Masked Studies,Method, Double-Blind,Method, Double-Masked,Methods, Double-Blind,Methods, Double-Masked,Studies, Double-Blind,Studies, Double-Masked,Study, Double-Blind,Study, Double-Masked
D004347	Drug Interactions	The action of a drug that may affect the activity, metabolism, or toxicity of another drug.	Drug Interaction,Interaction, Drug,Interactions, Drug