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The metastasizing pleomorphic adenoma of the salivary glands is a rare variant of pleomorphic adenoma with a benign microscopical appearance, but malignant biological behaviour and production of metastasis. The histopathological study with the routine techniques is not enough for disclosing the nature of these tumors and they are most of the times underdiagnosed as benign. The correct diagnosis, almost always too late, is evident after several recurrences and the detection of metastatic foci. The number of nucleolar organizing regions (NORs) detected with the silver colloid method can be used in histopathology to determine the degree of cell activity. We report the findings in a case of metastasizing pleomorphic adenoma of the submandibular gland. This technique demonstrated to be useful for the diagnosis and characterization of the metabolism of these tumors.
G Landini, and
M Kitano, and
A Urago
February 1989,
Human genetics,
G Landini, and
M Kitano, and
A Urago
April 1989,
Genetical research,
G Landini, and
M Kitano, and
A Urago
January 1986,
Cytogenetics and cell genetics,
G Landini, and
M Kitano, and
A Urago
January 1981,
American journal of human genetics,
G Landini, and
M Kitano, and
A Urago
January 2004,
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology,
G Landini, and
M Kitano, and
A Urago
August 1992,
Genetika,
G Landini, and
M Kitano, and
A Urago
January 1994,
Sao Paulo medical journal = Revista paulista de medicina,
G Landini, and
M Kitano, and
A Urago
April 2020,
Cells,
G Landini, and
M Kitano, and
A Urago
October 1979,
Human genetics,
G Landini, and
M Kitano, and
A Urago
January 1992,
Annales d'oto-laryngologie et de chirurgie cervico faciale : bulletin de la Societe d'oto-laryngologie des hopitaux de Paris,
