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We have screened patients of 14 families at risk for Duchenne muscular dystrophy (DMD) from the northern part of the German Democratic Republic using the cDNA clones Cf 23a and CF 56a. Of the 14 unrelated DMD families, 7 (50%) showed different deletions with these cDNA probes. A prenatal diagnosis by chorionic villi sampling was performed in a DMD family with patients showing a deletion of the 5.4 kb Pst I band detected by the cDNA probe Cf 56a. This band corresponds to a 10 kb exon region of the cDNA probe 8 of Koenig et al. The patient's mother was informative only for the flanking marker 99.6. The male fetus showed the same haplotype and the same deletion as the two patients.
F H Herrmann, and
K Wulff, and
M Schütz, and
M Wehnert
January 1991,
Neurologia croatica : glasilo Udruzenja neurologa Jugoslavije = official journal of Yugoslav Neurological Association,
F H Herrmann, and
K Wulff, and
M Schütz, and
M Wehnert
July 1988,
Prenatal diagnosis,
F H Herrmann, and
K Wulff, and
M Schütz, and
M Wehnert
March 1989,
Lancet (London, England),
F H Herrmann, and
K Wulff, and
M Schütz, and
M Wehnert
January 1989,
Journal of medical genetics,
F H Herrmann, and
K Wulff, and
M Schütz, and
M Wehnert
January 1987,
Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952),
F H Herrmann, and
K Wulff, and
M Schütz, and
M Wehnert
August 1986,
Neurology,
F H Herrmann, and
K Wulff, and
M Schütz, and
M Wehnert
July 1986,
Lancet (London, England),
F H Herrmann, and
K Wulff, and
M Schütz, and
M Wehnert
July 1977,
Lancet (London, England),
F H Herrmann, and
K Wulff, and
M Schütz, and
M Wehnert
January 1978,
Lancet (London, England),
F H Herrmann, and
K Wulff, and
M Schütz, and
M Wehnert
November 1977,
Lancet (London, England),
