A study was carried out to determine the prevalence and the species of liver flukes in indigenous adult cattle, to compare the diagnostic efficiency of fecal and post mortem examination and to assess the economic significance of bovine fasciolosis due to liver condemnation in the abattoir. Of the 406 livers and fecal samples examined, 57 (14.0%) and 20 (4.9%) were positive for fasciolosis. The most common liver fluke species affecting the cattle was Fasciola gigantica, 9.1% of cattle were infected with F. gigantica while, Fasciola. hepatica, mixed infections and unidentified or immature forms of Fasciola spp. were present in 3.2 %, 0.7% and 1 % of cattle, respectively. A retrospective abattoir survey revealed that the prevalence of fasciolosis was 12.7%. The prevalence of fasciolosis recorded in this study was lower than that reported by other researchers in this country. There was a strong relationship between fecal examination and postmortem findings of liver lesions, (K = 0.23) but under local conditions, postmortem examination was considered a better diagnostic tool for fasciolosis. Fasciolosis is of significant economic importance as the resultant liver condemnations caused an average loss of 4000 USD per annum. Hence, this disease deserves serious attention by the various stakeholders in order to promote the beef industry in the study area in particular and in the country in general.