Biomaterial Database

Asymmetric total synthesis and revised structure of cephalezomine H. 2009

Tsuyoshi Taniguchi, and Shin'ichi Yokoyama, and Hiroyuki Ishibashi

School of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan.

A revised structure of cephalezomine H, Cephalotaxus alkaloids, is presented. The originally assigned and revised structures of cephalezomine H were synthesized from the key intermediate for the synthesis of (-)-cephalotaxine.

UI	MeSH Term	Description	Entries
D006248	Harringtonines	Tetracyclic spiro-BENZAZEPINES isolated from the seeds of CEPHALOTAXUS. They are esters of the alkaloid cephalotaxine and may be effective as antineoplastic agents.	Cephalotaxine Alkaloids,Cephalotaxus Alkaloids,Alkaloids, Cephalotaxine,Alkaloids, Cephalotaxus
D013237	Stereoisomerism	The phenomenon whereby compounds whose molecules have the same number and kind of atoms and the same atomic arrangement, but differ in their spatial relationships. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)	Molecular Stereochemistry,Stereoisomers,Stereochemistry, Molecular,Stereoisomer
D015394	Molecular Structure	The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.	Structure, Molecular,Molecular Structures,Structures, Molecular
D032483	Cephalotaxus	A plant genus of the family TAXACEAE, order Pinales, class Pinopsida, division TRACHEOPHYTA. Members contain homoharringtonine.	Yew, Harrington Plum,Cephalotaxus harringtonia,Cephalotaxus harringtonias,Harrington Plum Yew,Harrington Plum Yews,Plum Yew, Harrington,Plum Yews, Harrington,Yews, Harrington Plum,harringtonias, Cephalotaxus