-transparent.png){kind=logo}
Expression of the oncogenes, epidermal growth factor (EGF) receptor, HER2/neu, c-myc, and c-fos, in renal cell carcinoma and corresponding nonneoplastic kidney tissue of 30 patients has been analyzed by Northern blot analysis. In renal cell carcinoma an inverse relationship of EGF receptor and HER2/neu gene expression was detected, with high expression of the EGF receptor gene in 22 of 30 (73%) cases and low expression of the HER2/neu gene in 28 of 30 (93%) cases. Furthermore, altered expression of the oncogenes c-myc and c-fos was detected in renal cell carcinoma, which appears to be related to the tumor grade of malignancy. Additional Southern blot analysis of six renal cell carcinomas gave no indication of chromosomal rearrangement events or gene amplification.
U Weidner, and
S Peter, and
T Strohmeyer, and
R Hussnätter, and
R Ackermann, and
H Sies
November 1989,
The Journal of urology,
U Weidner, and
S Peter, and
T Strohmeyer, and
R Hussnätter, and
R Ackermann, and
H Sies
January 1988,
Folia biologica,
U Weidner, and
S Peter, and
T Strohmeyer, and
R Hussnätter, and
R Ackermann, and
H Sies
January 1990,
The Journal of urology,
U Weidner, and
S Peter, and
T Strohmeyer, and
R Hussnätter, and
R Ackermann, and
H Sies
January 2011,
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie,
U Weidner, and
S Peter, and
T Strohmeyer, and
R Hussnätter, and
R Ackermann, and
H Sies
January 2022,
Journal of oral and maxillofacial pathology : JOMFP,
U Weidner, and
S Peter, and
T Strohmeyer, and
R Hussnätter, and
R Ackermann, and
H Sies
March 2010,
European journal of cancer (Oxford, England : 1990),
U Weidner, and
S Peter, and
T Strohmeyer, and
R Hussnätter, and
R Ackermann, and
H Sies
July 2016,
Journal of clinical and diagnostic research : JCDR,
U Weidner, and
S Peter, and
T Strohmeyer, and
R Hussnätter, and
R Ackermann, and
H Sies
January 2024,
Indian journal of urology : IJU : journal of the Urological Society of India,
U Weidner, and
S Peter, and
T Strohmeyer, and
R Hussnätter, and
R Ackermann, and
H Sies
June 1990,
International journal of cancer,
U Weidner, and
S Peter, and
T Strohmeyer, and
R Hussnätter, and
R Ackermann, and
H Sies
May 2012,
BMC research notes,
