[Use of inactivated vaccine against infectious rhinotracheitis--pustular vulvovaginitis (IBR-IPV) in calves and pregnant cows]. 1977

S Khristov, and I Karadzhov

A total of twelve batches of an inactivated vaccine against IBR--IPV, obtained by the authors, were tested in the practice. Vaccinated were 212 calves and 1172 cows and heifers on five dairy farms in different communities. On the basis of virologic, serologic, clinical and epizootiologic investigations the conclusions were drawn that the vaccine is harmless and highly immunogenic. In subcutaneous application at the rate of 3 cm3, twice, it renders protection against IBR--IPV infection (respiratory diseases and abortions) to calves aged more than 30 days for at least 6 months and 8 months for pregnant cows and heifers. On farms with a record of active IBP--IPV infection it is suggested to treat both the diseased and apparently (clinically) normal calves, either therapeutically or prophylactically, with a hyperimmune serum, and after the disease has receded--to resort to vaccination. In comparison with the live vaccines the tested one has been shown to provoke no postvaccinal accidents, eliminating the possibility of maintaining and widening the active infection foci, at otherwise almost comparable immunogenic properties as regards the titers of the virus-neutralizing antibodies produced after the vaccination.

UI MeSH Term Description Entries
D007109 Immunity Nonsusceptibility to the invasive or pathogenic effects of foreign microorganisms or to the toxic effect of antigenic substances. Immune Process,Immune Response,Immune Processes,Immune Responses,Process, Immune,Response, Immune
D007117 Immunization, Secondary Any immunization following a primary immunization and involving exposure to the same or a closely related antigen. Immunization, Booster,Revaccination,Secondary Immunization,Booster Immunization,Booster Immunizations,Immunizations, Booster,Immunizations, Secondary,Revaccinations,Secondary Immunizations
D007241 Infectious Bovine Rhinotracheitis A herpesvirus infection of CATTLE characterized by INFLAMMATION and NECROSIS of the mucous membranes of the upper RESPIRATORY TRACT. Bovine Rhinotracheitides, Infectious,Bovine Rhinotracheitis, Infectious,Infectious Bovine Rhinotracheitides,Rhinotracheitides, Infectious Bovine,Rhinotracheitis, Infectious Bovine
D007242 Herpesvirus 1, Bovine A species of VARICELLOVIRUS that causes INFECTIOUS BOVINE RHINOTRACHEITIS and other associated syndromes in CATTLE. IBR-IPV Virus,Infectious Bovine Rhinotracheitis Virus,Infectious Pustular Vulvovaginitis Virus,Bovine Herpesvirus 1,Bovine Rhinotracheitis Virus, Infectious,Herpesvirus 1 (alpha), Bovine,Pustular Vulvovaginitis Virus, Infectious,IBR IPV Virus,IBR-IPV Viruses,Virus, IBR-IPV,Viruses, IBR-IPV
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D002417 Cattle Domesticated bovine animals of the genus Bos, usually kept on a farm or ranch and used for the production of meat or dairy products or for heavy labor. Beef Cow,Bos grunniens,Bos indicus,Bos indicus Cattle,Bos taurus,Cow,Cow, Domestic,Dairy Cow,Holstein Cow,Indicine Cattle,Taurine Cattle,Taurus Cattle,Yak,Zebu,Beef Cows,Bos indicus Cattles,Cattle, Bos indicus,Cattle, Indicine,Cattle, Taurine,Cattle, Taurus,Cattles, Bos indicus,Cattles, Indicine,Cattles, Taurine,Cattles, Taurus,Cow, Beef,Cow, Dairy,Cow, Holstein,Cows,Dairy Cows,Domestic Cow,Domestic Cows,Indicine Cattles,Taurine Cattles,Taurus Cattles,Yaks,Zebus
D002418 Cattle Diseases Diseases of domestic cattle of the genus Bos. It includes diseases of cows, yaks, and zebus. Bovine Diseases,Bovine Disease,Cattle Disease,Disease, Bovine,Disease, Cattle,Diseases, Bovine,Diseases, Cattle
D005260 Female Females
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000917 Antibody Formation The production of ANTIBODIES by proliferating and differentiated B-LYMPHOCYTES under stimulation by ANTIGENS. Antibody Production,Antibody Response,Antibody Responses,Formation, Antibody,Production, Antibody,Response, Antibody,Responses, Antibody

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