Psychiatric symptoms in Parkinson's disease assessed with the SCL-90R self-reported questionnaire. 2010

Chiara Siri, and Roberto Cilia, and Danilo De Gaspari, and Federica Villa, and Stefano Goldwurm, and Catalano Marco, and Gianni Pezzoli, and Angelo Antonini
Parkinson Institute, Istituti Clinici di Perfezionamento, Via Bignami, 1, 20123, Milan, Italy. chiara.siri@parkinson.it

The frequency of psychopathological symptoms in patients with Parkinson's disease (PD) is often underestimated because of the lack of comprehensive evaluation tools. A total of 486 consecutive non-demented PD patients completed the Symptom Checklist 90 Revised (SCL-90R) self-reported questionnaire, a validated tool for the assessment of psychopathological symptoms on nine dimensions. Somatization, depression, anxiety and obsessive-compulsive behaviors were reported by nearly half of the PD patients. They were more likely to occur in females. Disease-related factors such as duration, severity and daily dosages, but not type of dopaminergic medications, were associated with the occurrence of these symptoms. Psychopathological features are frequent in PD and their occurrence is underlined by disease-related factors.

UI MeSH Term Description Entries
D008297 Male Males
D009771 Obsessive-Compulsive Disorder An anxiety disorder characterized by recurrent, persistent obsessions or compulsions. Obsessions are the intrusive ideas, thoughts, or images that are experienced as senseless or repugnant. Compulsions are repetitive and seemingly purposeful behavior which the individual generally recognizes as senseless and from which the individual does not derive pleasure although it may provide a release from tension. Anankastic Personality,Neurosis, Obsessive-Compulsive,Anankastic Personalities,Disorder, Obsessive-Compulsive,Disorders, Obsessive-Compulsive,Neuroses, Obsessive-Compulsive,Neurosis, Obsessive Compulsive,Obsessive Compulsive Disorder,Obsessive-Compulsive Disorders,Obsessive-Compulsive Neuroses,Obsessive-Compulsive Neurosis,Personalities, Anankastic,Personality, Anankastic
D010300 Parkinson Disease A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) Idiopathic Parkinson Disease,Lewy Body Parkinson Disease,Paralysis Agitans,Primary Parkinsonism,Idiopathic Parkinson's Disease,Lewy Body Parkinson's Disease,Parkinson Disease, Idiopathic,Parkinson's Disease,Parkinson's Disease, Idiopathic,Parkinson's Disease, Lewy Body,Parkinsonism, Primary
D011795 Surveys and Questionnaires Collections of data obtained from voluntary subjects. The information usually takes the form of answers to questions, or suggestions. Community Survey,Nonrespondent,Questionnaire,Questionnaires,Respondent,Survey,Survey Method,Survey Methods,Surveys,Baseline Survey,Community Surveys,Methodology, Survey,Nonrespondents,Questionnaire Design,Randomized Response Technique,Repeated Rounds of Survey,Respondents,Survey Methodology,Baseline Surveys,Design, Questionnaire,Designs, Questionnaire,Methods, Survey,Questionnaire Designs,Questionnaires and Surveys,Randomized Response Techniques,Response Technique, Randomized,Response Techniques, Randomized,Survey, Baseline,Survey, Community,Surveys, Baseline,Surveys, Community,Techniques, Randomized Response
D003863 Depression Depressive states usually of moderate intensity in contrast with MAJOR DEPRESSIVE DISORDER present in neurotic and psychotic disorders. Depressive Symptoms,Emotional Depression,Depression, Emotional,Depressive Symptom,Symptom, Depressive
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D000978 Antiparkinson Agents Agents used in the treatment of Parkinson's disease. The most commonly used drugs act on the dopaminergic system in the striatum and basal ganglia or are centrally acting muscarinic antagonists. Antiparkinson Drugs,Antiparkinsonian Agents,Antiparkinsonians,Agents, Antiparkinson,Agents, Antiparkinsonian,Drugs, Antiparkinson
D001007 Anxiety Feelings or emotions of dread, apprehension, and impending disaster but not disabling as with ANXIETY DISORDERS. Angst,Anxiousness,Hypervigilance,Nervousness,Social Anxiety,Anxieties, Social,Anxiety, Social,Social Anxieties

Related Publications

Chiara Siri, and Roberto Cilia, and Danilo De Gaspari, and Federica Villa, and Stefano Goldwurm, and Catalano Marco, and Gianni Pezzoli, and Angelo Antonini
November 1990, Psychological medicine,
Chiara Siri, and Roberto Cilia, and Danilo De Gaspari, and Federica Villa, and Stefano Goldwurm, and Catalano Marco, and Gianni Pezzoli, and Angelo Antonini
July 2010, Movement disorders : official journal of the Movement Disorder Society,
Chiara Siri, and Roberto Cilia, and Danilo De Gaspari, and Federica Villa, and Stefano Goldwurm, and Catalano Marco, and Gianni Pezzoli, and Angelo Antonini
January 2019, Movement disorders : official journal of the Movement Disorder Society,
Chiara Siri, and Roberto Cilia, and Danilo De Gaspari, and Federica Villa, and Stefano Goldwurm, and Catalano Marco, and Gianni Pezzoli, and Angelo Antonini
January 2015, PloS one,
Chiara Siri, and Roberto Cilia, and Danilo De Gaspari, and Federica Villa, and Stefano Goldwurm, and Catalano Marco, and Gianni Pezzoli, and Angelo Antonini
January 2020, Journal of Parkinson's disease,
Chiara Siri, and Roberto Cilia, and Danilo De Gaspari, and Federica Villa, and Stefano Goldwurm, and Catalano Marco, and Gianni Pezzoli, and Angelo Antonini
January 1994, Journal of substance abuse,
Chiara Siri, and Roberto Cilia, and Danilo De Gaspari, and Federica Villa, and Stefano Goldwurm, and Catalano Marco, and Gianni Pezzoli, and Angelo Antonini
November 2017, Western journal of nursing research,
Chiara Siri, and Roberto Cilia, and Danilo De Gaspari, and Federica Villa, and Stefano Goldwurm, and Catalano Marco, and Gianni Pezzoli, and Angelo Antonini
November 2008, European archives of psychiatry and clinical neuroscience,
Chiara Siri, and Roberto Cilia, and Danilo De Gaspari, and Federica Villa, and Stefano Goldwurm, and Catalano Marco, and Gianni Pezzoli, and Angelo Antonini
July 2002, Current neurology and neuroscience reports,
Chiara Siri, and Roberto Cilia, and Danilo De Gaspari, and Federica Villa, and Stefano Goldwurm, and Catalano Marco, and Gianni Pezzoli, and Angelo Antonini
February 2018, Progress in neuro-psychopharmacology & biological psychiatry,
Copied contents to your clipboard!