[Pseudotumoral-like recurrence of visceral leishmaniasis in a seven-year-old girl]. 2009

E Jeziorski, and C Blanchet, and C Ludwig, and M Lalande, and V Coste, and J Dereure, and M Rodière
CHU de Montpellier, Hôpital Arnaud de Villeneuve, Service de Pédiatrie III, 371, avenue du Doyen Gaston Giraud, 34295 Montpellier cedex 5. jezior@free.fr

Visceral leishmaniasis is endemic around Mediterranean and is considered by certain authors as an opportunist disease. We report on the case of a 7-year-old girl treated by anti-TNF for an idiopathic juvenile arthritis which has presented a visceral leishmaniasis. Four years later, she presented a pseudotumoral-like recurrence located in a nasal mucous membrane. Leishmania infantum is classically responsible for visceral leishmaniasis but pure mucocutaneous leishmaniasis has been described. It is, for our knowledge, the first observation of a recurrence of visceral leishmaniasis in a mucocutaneous location. Atypical leishmaniasis in the endemic zones can appear in immunodepressed patients and must be evoked when in doubt.

UI MeSH Term Description Entries
D007074 Immunoglobulin G The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B. Gamma Globulin, 7S,IgG,IgG Antibody,Allerglobuline,IgG(T),IgG1,IgG2,IgG2A,IgG2B,IgG3,IgG4,Immunoglobulin GT,Polyglobin,7S Gamma Globulin,Antibody, IgG,GT, Immunoglobulin
D007371 Interferon-gamma The major interferon produced by mitogenically or antigenically stimulated LYMPHOCYTES. It is structurally different from TYPE I INTERFERON and its major activity is immunoregulation. It has been implicated in the expression of CLASS II HISTOCOMPATIBILITY ANTIGENS in cells that do not normally produce them, leading to AUTOIMMUNE DISEASES. Interferon Type II,Interferon, Immune,gamma-Interferon,Interferon, gamma,Type II Interferon,Immune Interferon,Interferon, Type II
D007898 Leishmaniasis, Visceral A chronic disease caused by LEISHMANIA DONOVANI and transmitted by the bite of several sandflies of the genera Phlebotomus and Lutzomyia. It is commonly characterized by fever, chills, vomiting, anemia, hepatosplenomegaly, leukopenia, hypergammaglobulinemia, emaciation, and an earth-gray color of the skin. The disease is classified into three main types according to geographic distribution: Indian, Mediterranean (or infantile), and African. Black Fever,Kala-Azar,Fever, Black,Kala Azar,Visceral Leishmaniasis
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D004283 Dog Diseases Diseases of the domestic dog (Canis familiaris). This term does not include diseases of wild dogs, WOLVES; FOXES; and other Canidae for which the heading CARNIVORA is used. Canine Diseases,Canine Disease,Disease, Canine,Disease, Dog,Diseases, Canine,Diseases, Dog,Dog Disease
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000276 Adjuvants, Immunologic Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity. Immunoactivators,Immunoadjuvant,Immunoadjuvants,Immunologic Adjuvant,Immunopotentiator,Immunopotentiators,Immunostimulant,Immunostimulants,Adjuvant, Immunologic,Adjuvants, Immunological,Immunologic Adjuvants,Immunological Adjuvant,Adjuvant, Immunological,Immunological Adjuvants
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia

Related Publications

E Jeziorski, and C Blanchet, and C Ludwig, and M Lalande, and V Coste, and J Dereure, and M Rodière
January 1978, Transactions of the Royal Society of Tropical Medicine and Hygiene,
E Jeziorski, and C Blanchet, and C Ludwig, and M Lalande, and V Coste, and J Dereure, and M Rodière
January 2016, Case reports in infectious diseases,
E Jeziorski, and C Blanchet, and C Ludwig, and M Lalande, and V Coste, and J Dereure, and M Rodière
January 2011, Polish journal of pathology : official journal of the Polish Society of Pathologists,
E Jeziorski, and C Blanchet, and C Ludwig, and M Lalande, and V Coste, and J Dereure, and M Rodière
September 2012, Ugeskrift for laeger,
E Jeziorski, and C Blanchet, and C Ludwig, and M Lalande, and V Coste, and J Dereure, and M Rodière
May 1999, Pediatric pulmonology,
E Jeziorski, and C Blanchet, and C Ludwig, and M Lalande, and V Coste, and J Dereure, and M Rodière
May 2005, The Pediatric infectious disease journal,
E Jeziorski, and C Blanchet, and C Ludwig, and M Lalande, and V Coste, and J Dereure, and M Rodière
November 2002, The Pediatric infectious disease journal,
E Jeziorski, and C Blanchet, and C Ludwig, and M Lalande, and V Coste, and J Dereure, and M Rodière
November 1959, The Medical journal of Australia,
E Jeziorski, and C Blanchet, and C Ludwig, and M Lalande, and V Coste, and J Dereure, and M Rodière
October 2017, Ugeskrift for laeger,
E Jeziorski, and C Blanchet, and C Ludwig, and M Lalande, and V Coste, and J Dereure, and M Rodière
May 1959, The Journal of laryngology and otology,
Copied contents to your clipboard!