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STUDIES ON NATURAL IMMUNITY TO PNEUMOCOCCUS TYPE III : I. THE CAPACITY OF STRAINS OF PNEUMOCOCCUS TYPE III TO GROW AT 41 degrees C. AND THEIR VIRULENCE FOR RABBITS. 1936

J F Enders, and M F Shaffer
Department of Bacteriology and Immunology, The Harvard Medical School, Boston.

1. A correlation appears to exist between the failure of certain strains of Pneumococcus Type III to grow at 41 degrees C. and their lack of virulence for rabbits. 2. It is likely that the capacity to grow at 41 degrees C.-an attribute constantly but not exclusively associated with strains of Pneumococcus Type III virulent for rabbits-is a prerequisite, but not the sole factor, in determining their virulence for these animals.

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