BIOMAT Database Logo BIOMAT Database Logo

[Interrelations of cyclic adenosine monophosphate and calcium in regulating glycogen synthetase in developing skeletal and cardiac muscles in chickens]. 1977

L A Kuznetsova

The decrease of glycogen synthetase activity under the effect of Ca++ and cAMP is observed in the skeletal muscles of chick embryos only at the later stages of embryogenesis (15-18 days). In the cardiac muscle the activity of glycogen synthetase is inhibited by Ca++ apparently prior to the 12th day of development, long before the effect of cAMP which appears, as in the skeletal muscles, on the 18th day. Under the combined effect of cAMP and Ca++ in vitro and that of Ca++ and epinephrine in vivo, no additivity was observed. The possibility of Ca++ participation in the realization of catecholamine effect on the glycogen synthetase system of muscle and their interrelations with cAMP are discussed.

UI MeSH Term Description Entries
D009132 Muscles Contractile tissue that produces movement in animals. Muscle Tissue,Muscle,Muscle Tissues,Tissue, Muscle,Tissues, Muscle
D009206 Myocardium The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow. Muscle, Cardiac,Muscle, Heart,Cardiac Muscle,Myocardia,Cardiac Muscles,Heart Muscle,Heart Muscles,Muscles, Cardiac,Muscles, Heart
D002118 Calcium A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. Coagulation Factor IV,Factor IV,Blood Coagulation Factor IV,Calcium-40,Calcium 40,Factor IV, Coagulation
D002642 Chick Embryo The developmental entity of a fertilized chicken egg (ZYGOTE). The developmental process begins about 24 h before the egg is laid at the BLASTODISC, a small whitish spot on the surface of the EGG YOLK. After 21 days of incubation, the embryo is fully developed before hatching. Embryo, Chick,Chick Embryos,Embryos, Chick
D002645 Chickens Common name for the species Gallus gallus, the domestic fowl, in the family Phasianidae, order GALLIFORMES. It is descended from the red jungle fowl of SOUTHEAST ASIA. Gallus gallus,Gallus domesticus,Gallus gallus domesticus,Chicken
D006006 Glycogen Synthase An enzyme that catalyzes the transfer of D-glucose from UDPglucose into 1,4-alpha-D-glucosyl chains. EC 2.4.1.11. Glycogen (Starch) Synthase,Glycogen Synthetase,Glycogen Synthase I,Synthase D,Synthase I,UDP-Glucose Glycogen Glucosyl Transferase,Synthase, Glycogen,Synthetase, Glycogen,UDP Glucose Glycogen Glucosyl Transferase
D006321 Heart The hollow, muscular organ that maintains the circulation of the blood. Hearts
D000242 Cyclic AMP An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH. Adenosine Cyclic 3',5'-Monophosphate,Adenosine Cyclic 3,5 Monophosphate,Adenosine Cyclic Monophosphate,Adenosine Cyclic-3',5'-Monophosphate,Cyclic AMP, (R)-Isomer,Cyclic AMP, Disodium Salt,Cyclic AMP, Monoammonium Salt,Cyclic AMP, Monopotassium Salt,Cyclic AMP, Monosodium Salt,Cyclic AMP, Sodium Salt,3',5'-Monophosphate, Adenosine Cyclic,AMP, Cyclic,Adenosine Cyclic 3',5' Monophosphate,Cyclic 3',5'-Monophosphate, Adenosine,Cyclic Monophosphate, Adenosine,Cyclic-3',5'-Monophosphate, Adenosine,Monophosphate, Adenosine Cyclic
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D024510 Muscle Development Developmental events leading to the formation of adult muscular system, which includes differentiation of the various types of muscle cell precursors, migration of myoblasts, activation of myogenesis and development of muscle anchorage. Myofibrillogenesis,Myogenesis,Muscular Development,Development, Muscle,Development, Muscular

Related Publications

L A Kuznetsova
[Calcium-regulating systems and cyclic adenosine monophosphate in peptic ulcer].
January 1980, Terapevticheskii arkhiv,
L A Kuznetsova
Glycogen synthetase kinase 2 and adenosine 3':5'-cyclic monophosphate-independent protein kinase activities in rabbit skeletal muscle.
January 1975, Biochemical Society transactions,
L A Kuznetsova
Cyclic adenosine monophosphate and cardiac contractility.
April 1973, Circulation research,
L A Kuznetsova
Glycogen synthetase in developing and adult skeletal muscle.
May 1971, The Biochemical journal,
L A Kuznetsova
Factors affecting the activity of muscle glycogen synthetase. 3. The reaction with adenosine triphosphate Mg++, and cyclic 3'5'-adenosine monophosphate.
September 1966, Archives of biochemistry and biophysics,
L A Kuznetsova
Cell communication, calcium ion, and cyclic adenosine monophosphate.
October 1970, Science (New York, N.Y.),
L A Kuznetsova
[Characteristics of glycogen synthetase I from rabbit skeletal muscles].
December 1977, Biokhimiia (Moscow, Russia),
L A Kuznetsova
[Different behavior of the I and D form of glycogen synthetase in skeletal and cardiac muscles].
January 1971, Verhandlungen der Deutschen Gesellschaft fur Innere Medizin,
L A Kuznetsova
[Relation of synthesis and decomposition rates of cyclic adenosine-3', 5'-monophosphate (cyclAMP) in rabbit skeletal muscles].
January 1976, Doklady Akademii nauk SSSR,
L A Kuznetsova
Cardiac preservation with nitroglycerine and cyclic adenosine monophosphate.
January 1999, Transplantation proceedings,
Copied contents to your clipboard!