Studies which take into account the anisotropy of tissue dielectric properties for the numerical assessment of induced currents from low-frequency magnetic fields are scarce. In the present study, we compare the induced currents in two anatomical models, using the impedance method. In the first model, we assume that all tissues have isotropic conductivity, whereas in the second one, we assume anisotropic conductivity for the skeletal muscle. Results show that tissue anisotropy should be taken into account when investigating the exposure to low-frequency magnetic fields, because it leads to higher induced current values.