Amniotic fluid aspiration in cases of SIDS. 2010

Tony Fracasso, and Bernd Karger, and Mechtild Vennemann, and Thomas Bajanowski, and Ute Maria Golla-Schindler, and Heidi Pfeiffer
Institut für Rechtsmedizin, Universitätsklinikum Münster, Roentgenstrasse 23, Muenster, Germany. Tony.Fracasso@ukmuenster.de

The scope of this study was to evaluate the incidence and the eventual consequences of amniotic fluid aspiration (AFA) in cases of sudden infant death. Cases of sudden infant death syndrome (SIDS; n = 113: 39 females, 74 males; mean age 4.6 months) were compared to a control group of 39 cases of explained death (14 females, 25 males; mean age 5.6 months). In each case, sections of the lung stained with hematoxylin and eosin and with the immunohistochemical reaction 34BE12 specific for cytokeratins were available. The microscope slides were observed at x200 magnification and semi-quantitatively classified into four categories(-, +, ++, and +++). In both groups, rests of amniotic fluid could be observed up to the fourth month of life. The comparison between the two groups did not show any significant difference. In the SIDS group, immunohistochemical reactions with the antibodies CD68, MRP8, MRP14, 27E10, 25F9, CD3, CD20Cy, and CD45R0 were available for the lungs. Twelve cases with AFA were compared to a group of SIDS cases without AFA with similar age and pathological distribution to evaluate whether the presence of amniotic remnants induced inflammatory changes in the lungs. No differences emerged. This study shows that AFA is not a rare event. Even moderate to severe AFA does not necessary cause death. A correlation between AFA and SIDS could not be shown.

UI MeSH Term Description Entries
D007150 Immunohistochemistry Histochemical localization of immunoreactive substances using labeled antibodies as reagents. Immunocytochemistry,Immunogold Techniques,Immunogold-Silver Techniques,Immunohistocytochemistry,Immunolabeling Techniques,Immunogold Technics,Immunogold-Silver Technics,Immunolabeling Technics,Immunogold Silver Technics,Immunogold Silver Techniques,Immunogold Technic,Immunogold Technique,Immunogold-Silver Technic,Immunogold-Silver Technique,Immunolabeling Technic,Immunolabeling Technique,Technic, Immunogold,Technic, Immunogold-Silver,Technic, Immunolabeling,Technics, Immunogold,Technics, Immunogold-Silver,Technics, Immunolabeling,Technique, Immunogold,Technique, Immunogold-Silver,Technique, Immunolabeling,Techniques, Immunogold,Techniques, Immunogold-Silver,Techniques, Immunolabeling
D007223 Infant A child between 1 and 23 months of age. Infants
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D008168 Lung Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood. Lungs
D008297 Male Males
D008854 Microscopy, Electron Microscopy using an electron beam, instead of light, to visualize the sample, thereby allowing much greater magnification. The interactions of ELECTRONS with specimens are used to provide information about the fine structure of that specimen. In TRANSMISSION ELECTRON MICROSCOPY the reactions of the electrons that are transmitted through the specimen are imaged. In SCANNING ELECTRON MICROSCOPY an electron beam falls at a non-normal angle on the specimen and the image is derived from the reactions occurring above the plane of the specimen. Electron Microscopy
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000653 Amniotic Fluid A clear, yellowish liquid that envelopes the FETUS inside the sac of AMNION. In the first trimester, it is likely a transudate of maternal or fetal plasma. In the second trimester, amniotic fluid derives primarily from fetal lung and kidney. Cells or substances in this fluid can be removed for prenatal diagnostic tests (AMNIOCENTESIS). Amniotic Fluid Index,Amniotic Fluid Indices,Amniotic Fluids,Fluid Index, Amniotic,Fluid Indices, Amniotic,Fluid, Amniotic,Fluids, Amniotic,Index, Amniotic Fluid,Indices, Amniotic Fluid
D013398 Sudden Infant Death The abrupt and unexplained death of an apparently healthy infant under one year of age, remaining unexplained after a thorough case investigation, including performance of a complete autopsy, examination of the death scene, and review of the clinical history. (Pediatr Pathol 1991 Sep-Oct;11(5):677-84) Cot Death,Crib Death,SIDS,Death, Sudden Infant,SID,Sudden Infant Death Syndrome,Cot Deaths,Death, Cot,Death, Crib,Infant Death, Sudden

Related Publications

Tony Fracasso, and Bernd Karger, and Mechtild Vennemann, and Thomas Bajanowski, and Ute Maria Golla-Schindler, and Heidi Pfeiffer
March 1980, Pediatrie,
Tony Fracasso, and Bernd Karger, and Mechtild Vennemann, and Thomas Bajanowski, and Ute Maria Golla-Schindler, and Heidi Pfeiffer
December 1978, American journal of obstetrics and gynecology,
Tony Fracasso, and Bernd Karger, and Mechtild Vennemann, and Thomas Bajanowski, and Ute Maria Golla-Schindler, and Heidi Pfeiffer
April 1948, The New England journal of medicine,
Tony Fracasso, and Bernd Karger, and Mechtild Vennemann, and Thomas Bajanowski, and Ute Maria Golla-Schindler, and Heidi Pfeiffer
April 1959, Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie,
Tony Fracasso, and Bernd Karger, and Mechtild Vennemann, and Thomas Bajanowski, and Ute Maria Golla-Schindler, and Heidi Pfeiffer
June 1969, Akusherstvo i ginekologiia,
Tony Fracasso, and Bernd Karger, and Mechtild Vennemann, and Thomas Bajanowski, and Ute Maria Golla-Schindler, and Heidi Pfeiffer
July 1952, Ugeskrift for laeger,
Tony Fracasso, and Bernd Karger, and Mechtild Vennemann, and Thomas Bajanowski, and Ute Maria Golla-Schindler, and Heidi Pfeiffer
January 1982, Annales de biologie clinique,
Tony Fracasso, and Bernd Karger, and Mechtild Vennemann, and Thomas Bajanowski, and Ute Maria Golla-Schindler, and Heidi Pfeiffer
June 1971, Sanfujinka no jissai. Practice of gynecology and obstetrics,
Tony Fracasso, and Bernd Karger, and Mechtild Vennemann, and Thomas Bajanowski, and Ute Maria Golla-Schindler, and Heidi Pfeiffer
January 1993, Kinderkrankenschwester : Organ der Sektion Kinderkrankenpflege,
Tony Fracasso, and Bernd Karger, and Mechtild Vennemann, and Thomas Bajanowski, and Ute Maria Golla-Schindler, and Heidi Pfeiffer
July 1959, American journal of obstetrics and gynecology,
Copied contents to your clipboard!