Physical and chemical properties of superparamagnetic Fe-incorporated nano hydroxyapatite. 2009

Hong Jiang, and Yubao Li, and Yi Zuo, and Weihu Yang, and Li Zhang, and Jidong Li, and Li Wang, and Qin Zou, and Lin Cheng, and Junfeng Li
Research Center for Nano Biomaterials, Analytical and Testing Center Sichuan University, Chengdu 610064, PR China.

Nano hydroxyapatite (n-HA) crystals carrying incorporated Fe ions were designed and synthesized by a co-precipitation method. The microstructure and morphology as well as magnetic property of the Fe-incorporated n-HA crystals (denoted as n-Fe-HA) were characterized by TEM, XRD and VSM. The results showed that lattice substitution or incorporation had occurred between Fe ions and n-HA, which was quite different from the mechanical mixture of Fe3O4 nanoparticles and n-HA crystals. The n-Fe-HA with a synthetic molar ratio of 1:2 (calculated by Fe3O4:HA) exhibited a needle like crystal shape and relatively good crystallinity. However, when the molar ratio was up to 1:1, some Fe3O4 nanoparticles were separated from n-Fe-HA crystals. The magnetization measurements showed that n-Fe-HA crystals were in superparamagnetic state, proving that the existence of Fe ions in n-HA crystals contributed to the magnetic properties of n-Fe-HA crystals. As one component of biomedical composite, n-Fe-HA has a potential to promote bone regeneration.

UI MeSH Term Description Entries
D007501 Iron A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. Iron-56,Iron 56
D008280 Magnetics The study of MAGNETIC PHENOMENA. Magnetic
D008422 Materials Testing The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility. Biocompatibility Testing,Biocompatible Materials Testing,Hemocompatibility Testing,Testing, Biocompatible Materials,Testing, Hemocompatible Materials,Hemocompatibility Testings,Hemocompatible Materials Testing,Materials Testing, Biocompatible,Materials Testing, Hemocompatible,Testing, Biocompatibility,Testing, Hemocompatibility,Testing, Materials,Testings, Biocompatibility
D008968 Molecular Conformation The characteristic three-dimensional shape of a molecule. Molecular Configuration,3D Molecular Structure,Configuration, Molecular,Molecular Structure, Three Dimensional,Three Dimensional Molecular Structure,3D Molecular Structures,Configurations, Molecular,Conformation, Molecular,Conformations, Molecular,Molecular Configurations,Molecular Conformations,Molecular Structure, 3D,Molecular Structures, 3D,Structure, 3D Molecular,Structures, 3D Molecular
D010316 Particle Size Relating to the size of solids. Particle Sizes,Size, Particle,Sizes, Particle
D003460 Crystallization The formation of crystalline substances from solutions or melts. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Crystalline Polymorphs,Polymorphism, Crystallization,Crystal Growth,Polymorphic Crystals,Crystal, Polymorphic,Crystalline Polymorph,Crystallization Polymorphism,Crystallization Polymorphisms,Crystals, Polymorphic,Growth, Crystal,Polymorph, Crystalline,Polymorphic Crystal,Polymorphisms, Crystallization,Polymorphs, Crystalline
D013499 Surface Properties Characteristics or attributes of the outer boundaries of objects, including molecules. Properties, Surface,Property, Surface,Surface Property
D046911 Macromolecular Substances Compounds and molecular complexes that consist of very large numbers of atoms and are generally over 500 kDa in size. In biological systems macromolecular substances usually can be visualized using ELECTRON MICROSCOPY and are distinguished from ORGANELLES by the lack of a membrane structure. Macromolecular Complexes,Macromolecular Compounds,Macromolecular Compounds and Complexes,Complexes, Macromolecular,Compounds, Macromolecular,Substances, Macromolecular
D049329 Nanostructures Materials which have structured components with at least one dimension in the range of 1 to 100 nanometers. These include NANOCOMPOSITES; NANOPARTICLES; NANOTUBES; and NANOWIRES. Nanomaterials,Nanostructured Materials,Material, Nanostructured,Materials, Nanostructured,Nanomaterial,Nanostructure,Nanostructured Material
D017886 Durapatite The mineral component of bones and teeth; it has been used therapeutically as a prosthetic aid and in the prevention and treatment of osteoporosis. Calcium Hydroxyapatite,Hydroxyapatite,Hydroxylapatite,Alveograf,Calcitite,Interpore-200,Interpore-500,Osprovit,Ossein-Hydroxyapatite Compound,Ossopan,Osteogen,Periograf,Hydroxyapatite, Calcium,Interpore 200,Interpore 500,Interpore200,Interpore500,Ossein Hydroxyapatite Compound

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