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Eighteen consecutive hirsute women attending an endocrine clinic have been studied by measurement of the urinary pregnanetriol excretion before and following the concurrent administration of corticotrophin and metyrapone. An abnormal increment in pregnanetriol excretion was observed in 11 of these 18 patients. It is suggested that this is evidence that an adrenal abnormality, probably operative at the 21-hydroxylase level, might be a factor responsible for the hirsutism in these 11 patients. Five adrenalectomized women who were also studied showed no significant increase in urinary pregnanetriol excretion in response to concurrent corticotrophin and metyrapone administration.
W Van't Hoff, and
E J Bicknell, and
P M Horrocks, and
J A Fleetwood, and
M Inthuprapa, and
R Hall
February 1960,
The Journal of clinical endocrinology and metabolism,
W Van't Hoff, and
E J Bicknell, and
P M Horrocks, and
J A Fleetwood, and
M Inthuprapa, and
R Hall
January 1962,
Revista iberica de endocrinologia,
W Van't Hoff, and
E J Bicknell, and
P M Horrocks, and
J A Fleetwood, and
M Inthuprapa, and
R Hall
January 1973,
Steroids and lipids research,
W Van't Hoff, and
E J Bicknell, and
P M Horrocks, and
J A Fleetwood, and
M Inthuprapa, and
R Hall
April 1979,
Endokrinologie,
W Van't Hoff, and
E J Bicknell, and
P M Horrocks, and
J A Fleetwood, and
M Inthuprapa, and
R Hall
December 1966,
Nihon Naibunpi Gakkai zasshi,
W Van't Hoff, and
E J Bicknell, and
P M Horrocks, and
J A Fleetwood, and
M Inthuprapa, and
R Hall
October 1967,
Acta endocrinologica,
W Van't Hoff, and
E J Bicknell, and
P M Horrocks, and
J A Fleetwood, and
M Inthuprapa, and
R Hall
January 1964,
Acta medica Academiae Scientiarum Hungaricae,
W Van't Hoff, and
E J Bicknell, and
P M Horrocks, and
J A Fleetwood, and
M Inthuprapa, and
R Hall
March 1965,
Orvosi hetilap,
W Van't Hoff, and
E J Bicknell, and
P M Horrocks, and
J A Fleetwood, and
M Inthuprapa, and
R Hall
September 1957,
Lancet (London, England),
W Van't Hoff, and
E J Bicknell, and
P M Horrocks, and
J A Fleetwood, and
M Inthuprapa, and
R Hall
June 1970,
Revista argentina de endocrinologia y metabolismo,
