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The effects of biogenic amines on the formation of adenosine-3',5' monophosphate (cAMP) in the anterior pituitary of rats were investigated. Pituitary halves were preincubated in a Krebs-Ringer bicarbonate buffer (pH 7.4) containing theophylline (10(-2)M) at 37 degrees C for 30 minutes and incubated in a fresh buffer for 15 minutes after the addition of test substances. Noradrenaline at 4 X 10(-4)M and serotonin at 3.3 X 10(-4)M were effective in elevating cAMP, but dopamine at 2 X 20(-4)M was ineffective. The beta adrenergic blocking agent, propranolol, effectively antagonized the cAMP response to noradrenaline, but the alpha adrenergic blocking agent, phentolamine, did not. The serotonin antagonist, methysergide, remarkably antagonized the cAMP response to serotonin, but the alpha and beta adrenergic agents did not.
N Hanasaki, and
T Uemura, and
K Noma, and
K Nakao, and
S Yano
January 1976,
Acta biologica et medica Germanica,
N Hanasaki, and
T Uemura, and
K Noma, and
K Nakao, and
S Yano
January 1990,
Synapse (New York, N.Y.),
N Hanasaki, and
T Uemura, and
K Noma, and
K Nakao, and
S Yano
January 1976,
Endokrynologia Polska,
N Hanasaki, and
T Uemura, and
K Noma, and
K Nakao, and
S Yano
January 1970,
Advances in biochemical psychopharmacology,
N Hanasaki, and
T Uemura, and
K Noma, and
K Nakao, and
S Yano
February 1975,
Experimental neurology,
N Hanasaki, and
T Uemura, and
K Noma, and
K Nakao, and
S Yano
October 1968,
Nature,
N Hanasaki, and
T Uemura, and
K Noma, and
K Nakao, and
S Yano
April 1975,
Canadian journal of biochemistry,
N Hanasaki, and
T Uemura, and
K Noma, and
K Nakao, and
S Yano
November 1971,
FEBS letters,
N Hanasaki, and
T Uemura, and
K Noma, and
K Nakao, and
S Yano
January 1975,
Acta physiologica Polonica,
N Hanasaki, and
T Uemura, and
K Noma, and
K Nakao, and
S Yano
April 1979,
Comptes rendus des seances de l'Academie des sciences. Serie D, Sciences naturelles,
