BIOMAT Database Logo BIOMAT Database Logo

Maternal flaxseed diet during lactation alters milk composition and programs the offspring body composition, lipid profile and sexual function. 2010

A A Troina, and M S Figueiredo, and E G Moura, and G T Boaventura, and L L Soares, and L F M F Cardozo, and E Oliveira, and P C Lisboa, and M A R F Passos, and M C F Passos
Department of Physiological Sciences, State University of Rio de Janeiro, Brazil.

We evaluated the effects of maternal dietary flaxseed during lactation on milk composition, body composition and sexual function of the adult female offspring. The dams were fed a control casein diet (C) or flaxseed diet (F, 25%) throughout lactation. F mothers showed higher serum 17beta-estradiol (E2) and leptin at weaning. F mother's milk had lower total cholesterol (TC) and higher E2 and leptin. The offspring of F dams showed lower body mass (BM), body fat mass (BFM), visceral fat mass (VFM), TC and triglycerides (TG) and higher serum leptin and E2 at 21 days. F offspring showed delayed puberty onset. At 150 days, these offspring presented higher BFM, VFM, TC, TG, E2 and lower relative uterine weight and lower progesterone. In conclusion, flaxseed during lactation did affect the lipid profile, adipose tissue and sexual function in adulthood, probably due hyperestrogenism and hyperleptinemia at weaning.

UI MeSH Term Description Entries
D007774 Lactation The processes of milk secretion by the maternal MAMMARY GLANDS after PARTURITION. The proliferation of the mammary glandular tissue, milk synthesis, and milk expulsion or let down are regulated by the interactions of several hormones including ESTRADIOL; PROGESTERONE; PROLACTIN; and OXYTOCIN. Lactation, Prolonged,Milk Secretion,Lactations, Prolonged,Milk Secretions,Prolonged Lactation,Prolonged Lactations
D008055 Lipids A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed) Lipid
D008892 Milk The off-white liquid secreted by the mammary glands of humans and other mammals. It contains proteins, sugar, lipids, vitamins, and minerals. Cow Milk,Cow's Milk,Milk, Cow,Milk, Cow's
D001823 Body Composition The relative amounts of various components in the body, such as percentage of body fat. Body Compositions,Composition, Body,Compositions, Body
D001835 Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. Body Weights,Weight, Body,Weights, Body
D005260 Female Females
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012741 Sexual Maturation Achievement of full sexual capacity in animals and in humans. Sex Maturation,Maturation, Sex,Maturation, Sexual
D017208 Rats, Wistar A strain of albino rat developed at the Wistar Institute that has spread widely at other institutions. This has markedly diluted the original strain. Wistar Rat,Rat, Wistar,Wistar Rats
D050154 Adiposity The amount of fat or lipid deposit at a site or an organ in the body, an indicator of body fat status.

Related Publications

A A Troina, and M S Figueiredo, and E G Moura, and G T Boaventura, and L L Soares, and L F M F Cardozo, and E Oliveira, and P C Lisboa, and M A R F Passos, and M C F Passos
Maternal soybean diet during lactation alters breast milk composition and programs the lipid profile in adult male rat offspring.
May 2018, Endocrine,
A A Troina, and M S Figueiredo, and E G Moura, and G T Boaventura, and L L Soares, and L F M F Cardozo, and E Oliveira, and P C Lisboa, and M A R F Passos, and M C F Passos
Maternal flaxseed diet during lactation changes adrenal function in adult male rat offspring.
October 2015, The British journal of nutrition,
A A Troina, and M S Figueiredo, and E G Moura, and G T Boaventura, and L L Soares, and L F M F Cardozo, and E Oliveira, and P C Lisboa, and M A R F Passos, and M C F Passos
Maternal diet during pregnancy and lactation and cow's milk allergy in offspring.
May 2016, European journal of clinical nutrition,
A A Troina, and M S Figueiredo, and E G Moura, and G T Boaventura, and L L Soares, and L F M F Cardozo, and E Oliveira, and P C Lisboa, and M A R F Passos, and M C F Passos
Maternal lipid intake during pregnancy and lactation alters milk composition and production and litter growth in rats.
March 1997, The Journal of nutrition,
A A Troina, and M S Figueiredo, and E G Moura, and G T Boaventura, and L L Soares, and L F M F Cardozo, and E Oliveira, and P C Lisboa, and M A R F Passos, and M C F Passos
Maternal low-protein diet during lactation programmes body composition and glucose homeostasis in the adult rat offspring.
November 2007, The British journal of nutrition,
A A Troina, and M S Figueiredo, and E G Moura, and G T Boaventura, and L L Soares, and L F M F Cardozo, and E Oliveira, and P C Lisboa, and M A R F Passos, and M C F Passos
Short- and long-term effects of maternal nicotine exposure during lactation on body adiposity, lipid profile, and thyroid function of rat offspring.
September 2009, The Journal of endocrinology,
A A Troina, and M S Figueiredo, and E G Moura, and G T Boaventura, and L L Soares, and L F M F Cardozo, and E Oliveira, and P C Lisboa, and M A R F Passos, and M C F Passos
Flaxseed oil during lactation changes milk and body composition in male and female suckling pups rats.
July 2014, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association,
A A Troina, and M S Figueiredo, and E G Moura, and G T Boaventura, and L L Soares, and L F M F Cardozo, and E Oliveira, and P C Lisboa, and M A R F Passos, and M C F Passos
Maternal supplementation with a complex milk lipid mixture during pregnancy and lactation alters neonatal brain lipid composition but lacks effect on cognitive function in rats.
April 2010, Nutrition research (New York, N.Y.),
A A Troina, and M S Figueiredo, and E G Moura, and G T Boaventura, and L L Soares, and L F M F Cardozo, and E Oliveira, and P C Lisboa, and M A R F Passos, and M C F Passos
Different Protein Sources in the Maternal Diet of the Rat during Gestation and Lactation Affect Milk Composition and Male Offspring Development during Adulthood.
September 2021, Reproductive sciences (Thousand Oaks, Calif.),
A A Troina, and M S Figueiredo, and E G Moura, and G T Boaventura, and L L Soares, and L F M F Cardozo, and E Oliveira, and P C Lisboa, and M A R F Passos, and M C F Passos
Maternal diet and lipid composition of breast milk.
August 1973, Lancet (London, England),
Copied contents to your clipboard!