Hanja (Ideogram) alexia and agraphia in patients with semantic dementia. 2010

Mee Kyung Suh, and Eun-Joo Kim, and Byung Hwa Lee, and Sang Won Seo, and Juhee Chin, and Sue J Kang, and Duk L Na
Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

Posterior fusiform gyrus (BA 37) is responsible for Hanja (ideogram) alexia in stroke patients. Patients with semantic dementia (SD) have lesions in the basal temporal area. The close proximity in these two lesions and the fact that reading ideograms requires holistic processing as is necessary in recognition of objects, suggests a possibility that ideogram alexia/agraphia may occur in patients with SD. We established and carried out Hanja and Hangul (phonogram) reading/writing tasks on six SD patients and nine Alzheimer's disease (AD) patients as control to see if these two patient groups show dissociation in the two sets of tests. SPM analysis was performed on the SD patients' PET images to look for any dysfunctions in the posterior fusiform gyrus. The SD patients manifested Hanja alexia/agraphia whereas Hangul reading/writing ability was relatively preserved. There were group differences between SD and AD in the Hanja tasks but not in the Hangul tasks. The SPM analysis revealed no hypometabolism in the posterior fusiform gyrus, but only in the middle and the anterior part of the temporal gyrus. Dysfunction in the middle temporal gyrus (BA 21) may have disrupted the temporal lobe connections preventing the function of the posterior fusiform gyrus.

UI MeSH Term Description Entries
D007802 Language A verbal or nonverbal means of communicating ideas or feelings. Dialect,Dialects,Languages
D007807 Language Tests Tests designed to assess language behavior and abilities. They include tests of vocabulary, comprehension, grammar and functional use of language, e.g., Development Sentence Scoring, Receptive-Expressive Emergent Language Scale, Parsons Language Sample, Utah Test of Language Development, Michigan Language Inventory and Verbal Language Development Scale, Illinois Test of Psycholinguistic Abilities, Northwestern Syntax Screening Test, Peabody Picture Vocabulary Test, Ammons Full-Range Picture Vocabulary Test, and Assessment of Children's Language Comprehension. Language Comprehension Tests,Vocabulary Tests,Boston Diagnostic Aphasia Examination,Boston Naming Test,Comprehensive Aphasia Test,Multilingual Aphasia Examination,Language Test
D007839 Functional Laterality Behavioral manifestations of cerebral dominance in which there is preferential use and superior functioning of either the left or the right side, as in the preferred use of the right hand or right foot. Ambidexterity,Behavioral Laterality,Handedness,Laterality of Motor Control,Mirror Writing,Laterality, Behavioral,Laterality, Functional,Mirror Writings,Motor Control Laterality,Writing, Mirror,Writings, Mirror
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009483 Neuropsychological Tests Tests designed to assess neurological function associated with certain behaviors. They are used in diagnosing brain dysfunction or damage and central nervous system disorders or injury. Aphasia Tests,Cognitive Test,Cognitive Testing,Cognitive Tests,Memory for Designs Test,Neuropsychological Testing,AX-CPT,Behavioral Assessment of Dysexecutive Syndrome,CANTAB,Cambridge Neuropsychological Test Automated Battery,Clock Test,Cognitive Function Scanner,Continuous Performance Task,Controlled Oral Word Association Test,Delis-Kaplan Executive Function System,Developmental Neuropsychological Assessment,Hooper Visual Organization Test,NEPSY,Neuropsychologic Tests,Neuropsychological Test,Paced Auditory Serial Addition Test,Repeatable Battery for the Assessment of Neuropsychological Status,Rey-Osterrieth Complex Figure,Symbol Digit Modalities Test,Test of Everyday Attention,Test, Neuropsychological,Tests, Neuropsychological,Tower of London Test,Neuropsychologic Test,Test, Cognitive,Testing, Cognitive,Testing, Neuropsychological,Tests, Cognitive
D010364 Pattern Recognition, Visual Mental process to visually perceive a critical number of facts (the pattern), such as characters, shapes, displays, or designs. Recognition, Visual Pattern,Visual Pattern Recognition
D010775 Photic Stimulation Investigative technique commonly used during ELECTROENCEPHALOGRAPHY in which a series of bright light flashes or visual patterns are used to elicit brain activity. Stimulation, Photic,Visual Stimulation,Photic Stimulations,Stimulation, Visual,Stimulations, Photic,Stimulations, Visual,Visual Stimulations
D011237 Predictive Value of Tests In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test. Negative Predictive Value,Positive Predictive Value,Predictive Value Of Test,Predictive Values Of Tests,Negative Predictive Values,Positive Predictive Values,Predictive Value, Negative,Predictive Value, Positive
D011932 Reading Acquiring information from text.

Related Publications

Mee Kyung Suh, and Eun-Joo Kim, and Byung Hwa Lee, and Sang Won Seo, and Juhee Chin, and Sue J Kang, and Duk L Na
February 2002, Journal of Korean medical science,
Mee Kyung Suh, and Eun-Joo Kim, and Byung Hwa Lee, and Sang Won Seo, and Juhee Chin, and Sue J Kang, and Duk L Na
June 1975, Brain : a journal of neurology,
Mee Kyung Suh, and Eun-Joo Kim, and Byung Hwa Lee, and Sang Won Seo, and Juhee Chin, and Sue J Kang, and Duk L Na
January 1989, Neurologija,
Mee Kyung Suh, and Eun-Joo Kim, and Byung Hwa Lee, and Sang Won Seo, and Juhee Chin, and Sue J Kang, and Duk L Na
January 2012, Neurology international,
Mee Kyung Suh, and Eun-Joo Kim, and Byung Hwa Lee, and Sang Won Seo, and Juhee Chin, and Sue J Kang, and Duk L Na
April 2011, Irish medical journal,
Mee Kyung Suh, and Eun-Joo Kim, and Byung Hwa Lee, and Sang Won Seo, and Juhee Chin, and Sue J Kang, and Duk L Na
January 1992, Neuroradiology,
Mee Kyung Suh, and Eun-Joo Kim, and Byung Hwa Lee, and Sang Won Seo, and Juhee Chin, and Sue J Kang, and Duk L Na
December 1966, American journal of ophthalmology,
Mee Kyung Suh, and Eun-Joo Kim, and Byung Hwa Lee, and Sang Won Seo, and Juhee Chin, and Sue J Kang, and Duk L Na
May 1976, Neurology,
Mee Kyung Suh, and Eun-Joo Kim, and Byung Hwa Lee, and Sang Won Seo, and Juhee Chin, and Sue J Kang, and Duk L Na
October 1991, Neurology,
Mee Kyung Suh, and Eun-Joo Kim, and Byung Hwa Lee, and Sang Won Seo, and Juhee Chin, and Sue J Kang, and Duk L Na
November 2020, International journal of language & communication disorders,
Copied contents to your clipboard!