Biomaterial Database

Ectopic colonization of primordial germ cells in the chick embryo lacking the gonads. 1991

M Nakamura, and T Kuwana, and Y Miyayama, and K Yoshinaga, and T Fujimoto

Department of Anatomy, Kumamoto University Medical School, Japan.

Chick primordial germ cells (PGCs) first appear in the extraembryonic region in the early embryo, then temporarily circulate via the blood vascular system and finally migrate into the gonadal anlagen. In the present study, we examined the trend of ectopic distribution of PGCs in the chick embryo when its future gonadal region had been removed at an early stage. Embryos at stage 10, from which the caudal third region was excised, were incubated until they reached stages 14 to 20. In embryos at stage 14, about 80% of the total PGCs were found in the capillaries of the yolk sac, whereas others were observed in the head, mainly in the mesenchyme and small vessels close to the neural tube. From stage 18 onward, many PGCs accumulated in the embryo proper; about 90% of them colonized in the head region around the neural tube. These ectopic PGCs in the head were found in the capillaries, sometimes as thrombi or emerging from them into the adjacent mesenchyme. These results show that, when the chick embryo lacked gonads, the PGCs could be concentrated in the head region and migrated from the capillaries into the mesenchyme.

UI	MeSH Term	Description	Entries
D002465	Cell Movement	The movement of cells from one location to another. Distinguish from CYTOKINESIS which is the process of dividing the CYTOPLASM of a cell.	Cell Migration,Locomotion, Cell,Migration, Cell,Motility, Cell,Movement, Cell,Cell Locomotion,Cell Motility,Cell Movements,Movements, Cell
D002642	Chick Embryo	The developmental entity of a fertilized chicken egg (ZYGOTE). The developmental process begins about 24 h before the egg is laid at the BLASTODISC, a small whitish spot on the surface of the EGG YOLK. After 21 days of incubation, the embryo is fully developed before hatching.	Embryo, Chick,Chick Embryos,Embryos, Chick
D005314	Embryonic and Fetal Development	Morphological and physiological development of EMBRYOS or FETUSES.	Embryo and Fetal Development,Prenatal Programming,Programming, Prenatal
D005854	Germ Cells	The reproductive cells in multicellular organisms at various stages during GAMETOGENESIS.	Gamete,Gametes,Germ-Line Cells,Germ Line,Cell, Germ,Cell, Germ-Line,Cells, Germ,Cells, Germ-Line,Germ Cell,Germ Line Cells,Germ Lines,Germ-Line Cell
D006066	Gonads	The gamete-producing glands, OVARY or TESTIS.	Gonad
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia